Aims: To describe the diagnosis and therapeutic aspects of amebic liver abscesses.
Material And Methods: Retrospective study of 46 cases of amebic liver abcesses seen at Bouaké Teaching Hospital during the period from January 1997 to June 2002.
Results: Three clinical pictures were carried out: painful and feverish hepatomegaly (n=28, 60.9%), fever with pain of the right hypochondrium (n=3, 6.5%) and diffuse acute peritonitis (n=15, 32.6%). Forty-one liver abcesses were diagnosed with abdominal ultrasonography and the remaining 5 cases were diagnosed during laparotomy. Fifteen patients had peritonitis due to rupture of liver abcesses and one among them had a gangrenous left colon. Amoebiasis was diagnosed by positive amebic serology among all patients. All the patients received antibiotic treatment, 16 patients were treated by needle aspiration under ultrasound and 15 patients underwent a laparotomy. Post-operative morbidity was of 4 parietal suppurations. Morbidity of needle aspiration was nil. One death occurs as the consequence of hepatocellular insufficiency.
Conclusion: This study stresses ultrasound examination place in the diagnosis and the treatment of amebic liver abscess. Laparotomy is still performed to deal with complicated forms such as intraperitoeal rupture.
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Cureus
December 2024
Department of Anatomy, Ganesh Shankar Vidyarthi Memorial Medical College, Kanpur, IND.
Purpose Hepatic abscesses remain a significant clinical challenge due to high morbidity and mortality. This research aims to examine the etiological spectrum, management approaches, clinical features, and results in hepatic abscesses in a tertiary care facility in northern India, emphasizing the distinctions among pyogenic liver abscesses (PLAs) and amoebic liver abscesses (ALAs). Methods This retrospective study was done at GSVM Medical College, Kanpur, analyzing 725 patients with hepatic abscesses over a 10-year period.
View Article and Find Full Text PDFWorld J Hepatol
December 2024
Department of Surgery, University of Witwatersrand, School of Clinical Medicine, Johannesburg 2193, Gauteng, South Africa.
Background: Hepatic abscesses represent infections of the liver parenchyma from bacteria, fungi, and parasitic organisms. Trends in both abscess microbiology and management of abscesses (infective collections) have changed over the past decade. There is a paucity of published data regarding the clinicopathological features of liver abscesses in sub-Saharan Africa and other low-income and middle-income countries.
View Article and Find Full Text PDFFront Cell Infect Microbiol
January 2025
Department of Biomedical Science and Technology, School of Biological Sciences, Ramakrishna Mission Vivekananda Educational and Research Institute (RKMVERI), Kolkata, India.
Amoebae, fascinatingly diverse protists, showcase a dual nature that positions them as both friends and foes in our world. These organisms, defined by their distinctive pseudopodia, span a spectrum from harmful to helpful. On the darker side, species like pose serious health risks, causing intestinal and liver diseases, while the infamous "brain-eating" leads to fatal primary amoebic meningoencephalitis (PAM), with a daunting 97% mortality rate.
View Article and Find Full Text PDFTrop Doct
January 2025
MD, Senior Resident, Department of Gastroenterology, All India Institute of Medical Sciences, Patna, Bihar, India.
Amoebic liver abscess (ALA), a common tropical infection, is caused by (EH). For decades, the first-line treatment for ALA has been metronidazole which has several drawbacks. The thioredoxin reductase enzyme in EH is essential for its anti-oxidative defence and survival during tissue invasion.
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