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| http://dx.doi.org/10.1503/cmaj.071891 | DOI Listing |
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Household waste-specific ambient air shows greater inhalable antimicrobial resistance risks in densely populated communities.
Waste Manag
January 2025
Shanghai Engineering Research Center of Biotransformation of Organic Solid Waste, School of Ecological and Environmental Science, East China Normal University, Shanghai 200241, PR China; Chongqing Key Laboratory of Precision Optics, Chongqing Institute of East China Normal University, Chongqing 401120, PR China. Electronic address:
Household waste is a hotspot of antibiotic resistance, which can be readily emitted to the ambient airborne inhalable particulate matters (PM) during the day-long storage in communities. Nevertheless, whether these waste-specific inhalable antibiotic resistance genes (ARGs) are associated with pathogenic bacteria or pose hazards to local residents have yet to be explored. By high-throughput metagenomic sequencing and culture-based antibiotic resistance validation, we analyzed 108 airborne PM and nearby environmental samples collected across different types of residential communities in Shanghai, the most populous city in China.
View Article and Find Full Text PDFEicosapentaenoic Acid and Docosahexaenoic Acid as an Antimicrobial Agent in Orthopedics-An In Vitro Study About the Race for Surface.
Pathogens
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Research Laboratory for Biofilms and Implant Associated Infections (BIOFILM LAB), University Hospital for Orthopaedics and Traumatology, Medical University of Innsbruck, Müllerstraße 44, 6020 Innsbruck, Austria.
Background: The burden of prosthetic joint infection in combination with antibiotic-resistant bacterial strains is a rising dilemma for patients experiencing total joint replacements. Around 0.8-2% of patients experience prosthetic joint infections, while up to 21% of patients are considered fatal cases after 5 years.
View Article and Find Full Text PDFCharacterization of Phage Endolysin PlyDolk21.
Antibiotics (Basel)
January 2025
Department of Food Science and Biotechnology, Research Institute of Food and Biotechnology, Seoul National University of Science and Technology, Seoul 01811, Republic of Korea.
is a significant cause of food poisoning. Broad-spectrum antibiotics, commonly used to control , are becoming less effective due to the rise of antibiotic-resistant strains, necessitating alternative control strategies. A -infecting bacteriophage, Dolk21, and its endolysin, PlyDolk21, were isolated and characterized.
View Article and Find Full Text PDFGreen Tea Extract (; L.): A Promising Antimicrobial, Anti-Quorum Sensing and Antibiofilm Candidate Against Multidrug-Resistant Species.
Antibiotics (Basel)
January 2025
Department of Microbiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt.
Background: Thermophilic species are among the main culprits behind bacterial gastroenteritis globally and have grown progressively resistant to clinically important antimicrobials. Many studies have been carried out to explore innovative and alternative strategies to control antibiotic-resistant campylobacters in animal reservoirs and human hosts; however, limited studies have been performed to develop efficient control schemes against biofilms.
Methods: This study investigated the antimicrobial and antibiofilm activities of some herbal extracts against multidrug-resistant (MDR) species recovered from different sources using phenotypic and molecular techniques.
Interference of Celastrol with Cell Wall Synthesis and Biofilm Formation in .
Antibiotics (Basel)
January 2025
Departamento de Bioquímica, Microbiología, Biología Celular y Genética, Facultad de Farmacia, Universidad de La Laguna, Avenida Astrofísico Fco Sánchez s/n, 38206 La Laguna, Spain.
: The emergence of antibiotic-resistant bacteria, including , underscores the need for novel antimicrobial agents. Celastrol, a natural compound derived from the plants of the Celastraceae family, has demonstrated promising antibacterial and antibiofilm properties against various pathogens. This study aims to evaluate the antibacterial effects, mechanism of action, and antibiofilm activity of celastrol against , an emerging opportunistic pathogen.
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