AI Article Synopsis
- Minimally invasive brain tumour surgery seeks to remove as much harmful tissue as possible while preserving vital brain functions, necessitating an understanding of the tumor's location relative to critical brain areas.
- Functional magnetic resonance imaging (fMRI) is highlighted as a valuable tool for mapping these relationships due to its non-invasive nature and preoperative accessibility, with particular emphasis on its applications in motor and language functioning.
- The review also discusses the validation of fMRI findings against invasive techniques, potential limitations of fMRI, and future directions for enhancing its use in presurgical planning.
Article Abstract
Minimally invasive resection of brain tumours aims at removing as much pathological tissue as possible while preserving essential brain functions. Therefore, the precise spatial relationship between the lesion and adjacent functionally essential brain parenchyma needs to be known. Functional magnetic resonance imaging (fMRI) is increasingly being used for this purpose because of its non-invasiveness, its relatively high spatial resolution and the preoperative availability of the results. In this review, the goals of fMRI at various key points during the management of patients with a brain tumour are discussed. Further, several practical aspects associated with fMRI for motor and language functioning are summarised, and the validation of the fMRI results with standard invasive mapping techniques is addressed. Next, several important pitfalls and limitations that warrant careful interpretations of the fMRI results are highlighted. Finally, two important future perspectives of presurgical fMRI are emphasised.
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| http://dx.doi.org/10.1007/s00330-009-1429-z | DOI Listing |
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