Ninety-eight patients were exposed to low-energy laser irradiation. Of these 52 and 31 had duodenal ulcer in aggravation phase with mucosal erosion and without it, respectively, 15 patients developed isolated erosive lesions of gastroduodenal mucosa. The energy was delivered to the target cites optically using fiber optics endoscope. Microcirculation was studied by bulbar biomicroscopy. Therapeutic response in the laser utilization proved positive being the highest for patients with a short disease history, moderate signs, small-size lesions. Normal microcirculation was not achieved though there was a trend to its improvement.

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