Autonomic hyperreflexia or autonomic dysreflexia is a syndrome seen in approximately 85% of all quadriplegic patients and constitutes the only medical emergency related to spinal cord injury. We report on a paraplegic patient with a C5 to C7 spinal cord injury who suffered autonomic hyperreflexia during percutaneous nephrolithotomy for a right renal stone. The reflex-induced hypertension subsided with termination of the operation, and administration of an alpha and beta-adrenergic blocking agent (labelatol hydrochloride). The stone was removed successfully by pyelolithotomy with the patient under general anesthesia 4 days later.
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http://dx.doi.org/10.1016/s0022-5347(17)38180-6 | DOI Listing |
PM R
January 2025
Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, Minnesota, USA.
Background: Individuals with spinal cord injury (SCI) commonly have autonomic dysreflexia (AD) with increased sympathetic activity. After SCI, individuals have decreased baroreflex sensitivity and increased vascular responsiveness.
Objective: To evaluate the relationship between baroreflex and blood vessel sensitivity with AD symptoms.
Cureus
November 2024
Intermediate Care Unit, Unidade Local de Saúde do Alto Minho, Viana do Castelo, PRT.
Serotonin syndrome (SS) is a potentially life-threatening condition caused by excessive serotonergic activity, often due to drug interactions. It classically manifests with autonomic and neuromuscular hyperactivity and by mental status changes that might include restlessness, delirium, and agitation. We present a case of a 76-year-old patient with Parkinson's disease with SS triggered by interaction between rasagiline and buspirone.
View Article and Find Full Text PDFPM R
December 2024
Department of Medicine, University of Montreal, Montreal, Quebec, Canada.
Top Spinal Cord Inj Rehabil
December 2024
James J. Peters VA Medical Center, Bronx, New York.
Cureus
October 2024
Medicine, Faculty of Medical Sciences, Colombo South Teaching Hospital - Kalubowila, University of Sri Jayewardenepura, Colombo, LKA.
Tetanus, caused by , remains a serious but preventable infection, with global incidence significantly reduced through widespread vaccination. We present the case of a 51-year-old man who developed severe tetanus following a minor nail prick injury, despite receiving tetanus toxoid and antibiotics. His condition rapidly progressed to trismus, hyperreflexia, continuous spasms, autonomic instability, and respiratory failure, requiring mechanical ventilation.
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