A microreactor with thousands of subcompartments: enzyme-loaded liposomes within polymer capsules.

Angew Chem Int Ed Engl

Centre for Nanoscience and Nanotechnology, Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia.

Published: September 2009

Fully loaded: Noncovalent anchoring of liposomes into polymer multilayered films with cholesterol-modified polymers allows the preparation of capsosomes-liposome-compartmentalized polymer capsules (see picture). A quantitative enzymatic reaction confirmed the presence of active cargo within the capsosomes and was used to determine the number of subcompartments within this novel biomedical carrier system.

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http://dx.doi.org/10.1002/anie.200900386DOI Listing

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