The purpose of this retrospective study was to review the paediatric experience in Edinburgh of a relatively benign skin tumour. The study group consisted of children less than 13 years of age with a pathological diagnosis of pilomatrixoma over the period between January 1980 and December 1989. The results reaffirmed a female preponderance. The majority of lesions had been present for less than 1 year at the time of removal but were mainly misdiagnosed at the time of primary consultation or at removal. Although pilomatrixoma has a 'typical' appearance pathologically there are problems with preoperative diagnosis. Sites of occurrence are comparable with the dermoid type of cyst and the possibility must be considered of an embryological origin for pilomatrixoma.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Pilomatrix Carcinoma of Infrequent Localization.
Skinmed
January 2025
Dermatology Department, Miguel Servet Hospital, IIS Aragon, Zaragoza University, Zaragoza, Spain.
A 63-year-old man, with no past medical history, presented with an asymptomatic, progressively evolving polypoid lesion for 2 years in the left ciliary region. Physical examination revealed an exophytic tumor lesion of firm consistency and lobulated surface, with regular and well-defined borders. It measured 2 cm in diameter, and had a brownish-violet coloration with whitish areas (Figure 1).
View Article and Find Full Text PDFClinical and Histopathological Perspectives of Pilomatrixoma: A Case Report.
Indian J Otolaryngol Head Neck Surg
December 2024
Department of ENT and Head-Neck Surgery, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, India.
Article Synopsis
- Pilomatrixoma is a rare, benign tumor from hair follicle cells, mostly seen in kids and young adults, exemplified by an 8-year-old boy with a growing neck lump over three months.* -
- A fine-needle aspiration showed characteristics of an adnexal tumor, leading to surgical removal, which confirmed the diagnosis of pilomatrixoma through histopathology.* -
- The case underscores the need for combined clinical and lab evaluation for accurate diagnosis and highlights successful surgery as key to preventing recurrence, providing valuable insights for pediatric care.*
Atypical and giant proliferating pilomatrixoma of the eyelid: a clinicopathological report.
BMC Ophthalmol
November 2024
Department of Oculo-Facial Plastic and Reconstructive Surgery, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Background: Pilomatrixoma is an uncommon benign skin neoplasm originating from the hair follicle. Here, we report a rare case of giant and atypical proliferating pilomatrixoma affecting the eyelid.
Case Presentation: A 47-year-old male presented with a solitary, giant mass on his left upper eyelid, which had recently shown progressive enlargement.
High-grade Endometrial Carcinomas With Solid Basaloid Morphology and Geographic Necrosis Lacking Definitive Pilomatrix-like Features: Clinicopathologic Characteristics Including Aggressive Behavior and Novel Molecular Events.
Int J Gynecol Pathol
October 2024
Department of Pathology.
Article Synopsis
- High-grade endometrioid carcinomas can exhibit a solid basaloid morphology with geographic necrosis (SB-GN), which is a key characteristic of a new tumor type called pilomatrix-like high-grade endometrioid carcinoma (PiMHEC).
- A study screened 300 endometrial carcinomas for SB-GN, identifying four cases (1.3%) that demonstrated this pattern, all exhibiting aggressive behaviors despite some being mismatch repair (MMR) deficient.
- One SB-GN case met most diagnostic criteria for PiMHEC, revealing notable genetic mutations but lacking the typical shadow cells; molecular analyses indicated novel variants, suggesting SB-GN may indicate poor prognosis and potential treatment implications.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!