We use collinear spatially resolved spectral interferometery to characterize the nonlinear phase changes experienced by an intense ultrashort pulse propagating in glass. The measurement yields the spectrally dependent wavefront, allowing us to measure the spatial and chromatic aberrations of the nonlinearly induced lens. For these conditions, we find that while the shape of the spatial wavefront follows the beam profile as expected, the spectral dependence of the lensing power is determined by the self-phase modulation. The simultaneous measurement of the nonlinear spatiospectral phase demonstrates how the nonlinear spectral phase is coupled to self-focusing.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1364/ol.34.001294 | DOI Listing |
Magn Reson Med
February 2025
Department of Bioengineering, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.
Purpose: To develop and evaluate a novel method for computationally efficient reconstruction from noisy MR spectroscopic imaging (MRSI) data.
Methods: The proposed method features (a) a novel strategy that jointly learns a nonlinear low-dimensional representation of high-dimensional spectroscopic signals and a neural-network-based projector to recover the low-dimensional embeddings from noisy/limited data; (b) a formulation that integrates the forward encoding model, a regularizer exploiting the learned representation, and a complementary spatial constraint; and (c) a highly efficient algorithm enabled by the learned projector within an alternating direction method of multipliers (ADMM) framework, circumventing the computationally expensive network inversion subproblem.
Results: The proposed method has been evaluated using simulations as well as in vivo H and P MRSI data, demonstrating improved performance over state-of-the-art methods, with about 6 fewer averages needed than standard Fourier reconstruction for similar metabolite estimation variances and up to 100 reduction in processing time compared to a prior neural network constrained reconstruction method.
J Phys Chem B
June 2023
Department of Chemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Raman spectroscopy has long been known to provide sufficient information to discriminate distinct cell phenotypes. Underlying this discriminating capability is that Raman spectra provide an overall readout of the metabolic profiles that change with transcriptomic activity. Robustly associating Raman spectral changes with the regulation of specific signaling pathways may be possible, but the spectral signals of interest may be weak and vary somewhat among individuals.
View Article and Find Full Text PDFJ Phys Chem A
September 2022
Physical Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999, Richland, Washington 99352, United States.
Nat Commun
July 2022
School of Information Technology and Electrical Engineering, The University of Queensland, Brisbane, QLD, 4072, Australia.
Measuring polarisation, spectrum, temporal dynamics, and spatial complex amplitude of optical beams is essential to studying phenomena in laser dynamics, telecommunications and nonlinear optics. Current characterisation techniques apply in limited contexts. Non-interferometric methods struggle to distinguish spatial phase, while phase-sensitive approaches necessitate either an auxiliary reference source or a self-reference, neither of which is universally available.
View Article and Find Full Text PDFIEEE Trans Biomed Eng
October 2022
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!