The Wingate anaerobic test (WAnT) has not been used to assess individuals with Down syndrome (DS) and it is unknown if it is reliable in this population. We investigated the reliability of the WAnT in 19 adolescents with DS (age = 14.8 yrs; weight = 52.7 kg; height = 146.3 cm). Participants completed, on separate days, two standards WAnT using a resistance of 0.7 Nm x body weight (kg) in individuals > 14 years old, and 0.5 Nm x body weight (kg) in participants < 14 years of age. Data were analyzed using intraclass correlation coefficient (ICC), dependent t tests and Bland-Altman plots. There was a significant difference between days for peak power (210.37 W vs. 236.26 W; ICC = 0.93), but not for mean power (158.72 vs. 168.71 W; ICC = 0.86), time to peak power (6.67 vs. 6.28 s; ICC = 0.69), or the fatigue index (9.33 vs. 5.43 W/sec; ICC = 0.09). Adolescents with DS exhibit low WAnT performance compared with previously published data on adolescents without DS and the reliability of WAnT is questionable in this population.
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http://dx.doi.org/10.1123/pes.21.1.47 | DOI Listing |
BMC Gastroenterol
January 2025
Department of Nephrology, QingPu Branch of Zhongshan Hospital Affiliated to Fudan University, Shanghai, People's Republic of China.
Background: Gallstone disease (GSD) is associated with obesity. The Cardiometabolic Index (CMI), a metric that accurately assesses central adiposity and visceral fat, has not been extensively studied in relation to GSD risk. This study investigates the link between CMI and GSD incidence in U.
View Article and Find Full Text PDFBMC Public Health
January 2025
Early Start, Faculty of the Arts, Social Sciences and Humanities, University of Wollongong, Wollongong, NSW, 2522, Australia.
Introduction: The relationship between 24-h movement behaviours (i.e. sleep, sedentary behaviour and physical activity) and adiposity in preschoolers remains unclear.
View Article and Find Full Text PDFBMC Womens Health
January 2025
Post Graduate School of Public Health, University of Siena, Siena, 53100, Italy.
Menarche is an important period in a female's life; its time of onset may depend on various factors and could correlate with the development of diseases in adulthood. Our study aims to investigate the relationship between body mass index and age at onset of menarche; METHODS: We used a unique standardized national dataset on adolescent girls participating in the Italian Health Behaviour in School-aged Children Study. Two independent nationally representative survey datasets: one on 15-year-olds (n = 6505, year 2017/2018) and one on 11-year-olds (n = 6548, year 2013/2014) were analysed.
View Article and Find Full Text PDFBMC Pediatr
January 2025
Institute of Pediatric Endocrinology, Dana Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, 6423906, Tel Aviv, Israel.
Background: The diagnosis of depression or anxiety treated by SSRIs has become relatively common in women of childbearing age. However, the impact of gestational SSRI treatment on newborn thyroid function is lacking. We explored the impact of gestational SSRI treatment on newborn thyroid function as measured by the National Newborn Screening (NBS) Program and identified contributory factors.
View Article and Find Full Text PDFPharmacol Rep
January 2025
Department of Gynaecological Oncology, Poznań University Clinical Hospital, Szamarzewskiego 84, Poznań, Poland.
Background: Olaparib is a relatively new poly(ADP-ribose) polymerase inhibitor (PARPi) administered to ovarian cancer (OC) patients with a complete or partial response to first-line chemotherapy. One of the metabolic side effects of olaparib is the disruption of glucose homeostasis, often resulting in hyperglycemia The study was a retrospective analysis of olaparib-induced hyperglycemia in OC patients with initial normoglycemia following the first, second, and third month of olaparib treatment METHODS: The study involved 32 OC patients, classified into three groups according to their Body Mass Index (BMI): normal BMI (BMI 18.5-24.
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