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Prevalence of Infection in Pregnant Women and Risk of Vertical Transmission in Newborns in Chiapas, Mexico.
Trop Med Infect Dis
November 2024
Faculty of Health Science, Anahuac Mexico University, Av. Anahuac University 46, Lomas Anáhuac, Huixquilucan, Estado de México, Huixquilucan 52786, Mexico.
Article Synopsis
- Chiapas is a key area for Chagas disease due to infected animals and insects, but there's a lack of effective monitoring for the disease.
- A study tested 193 pregnant women in Tuxtla Gutierrez to find out how common Chagas disease was and whether it could spread to newborns.
- The results showed that 32.12% of the pregnant women were infected, with 8% of their newborns also testing positive for the disease.
Teratogenic parasites: disease mechanisms and emerging study models.
Trends Parasitol
December 2024
Department of Biological Sciences, Dietrich School of Arts and Sciences, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:
Congenital infections are a leading preventable cause of pregnancy complications impacting both mother and fetus. Although advancements have been made in understanding various congenital infections, the mechanisms of parasitic infections during pregnancy remain poorly understood. This review covers the global incidence of three parasites capable of congenital transmission - Trypanosoma cruzi, Plasmodium spp.
View Article and Find Full Text PDFHealth experiences of pregnant and women with chagas disease in the Atacama, Tarapaca, and Metropolitan regions of Chile. Mistreatment as an indicator of healthcare barriers.
PLoS One
November 2024
School Museum studies, University of Leicester, Leicester, United Kingdom.
Article Synopsis
- Congenital transmission of Trypanosoma cruzi is a significant health issue, especially for migrant women in Chile who face barriers in accessing healthcare due to unrecognized health rights.
- A qualitative study involving 54 in-depth interviews unveils how women living with Chagas disease experience healthcare, highlighting the importance of effective communication in their treatment and diagnosis.
- The results reveal that empathetic communication from healthcare providers can enhance patient acceptance and treatment continuity, while poor communication can lead to distrust and avoidance of the healthcare system.
-derived exovesicles contribute to parasite infection, tissue damage, and apoptotic cell death during infection of human placental explants.
Front Cell Infect Microbiol
October 2024
Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
, the causative agent of Chagas disease, can be congenitally transmitted by crossing the placental barrier. This study investigates the role of -derived exovesicles (TcEVs) in facilitating parasite infection and the consequent tissue damage and apoptotic cell death in human placental explants (HPEs). Our findings demonstrate that TcEVs significantly enhance the parasite load and induce tissue damage in HPEs, both in the presence and absence of the parasite.
View Article and Find Full Text PDFNewborns with microcephaly in Brazil and potential vertical transmission of Oropouche virus: a case series.
Lancet Infect Dis
October 2024
Department of Arbovirology and Hemorrhagic Fever, Evandro Chagas Institute, Ananindeua, Pará, Brazil. Electronic address:
Background: Oropouche fever, an orthobunyavirus disease endemic in Brazilian Amazon, has caused many febrile epidemics. In 2024, an epidemic of Oropouche fever spread in Brazil, with more than 7930 cases reported between Jan 1 and Aug 31. Infections in pregnant people have suggested the possibility of negative fetal consequences, therefore we tested newborns with microcephaly for known congenital pathogens and Oropouche virus (OROV).
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