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[111In-DTPAOC SPECT-CT in radiation pulmonary fibrosis].
Rev Esp Med Nucl
July 2009
Servicio de Medicina Nuclear, HCU Lozano Blesa, Zaragoza, Spain.
Comparison of 68Ga-DOTATOC PET and 111In-DTPAOC (Octreoscan) SPECT in patients with neuroendocrine tumours.
Eur J Nucl Med Mol Imaging
October 2007
Department of Nuclear Medicine, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.
Purpose: Neuroendocrine tumours (NETs) can be imaged with scintigraphy using radiolabelled somatostatin analogues. The aim of our study was to compare the value of (68)Ga-DOTATOC PET and (111)In-DTPAOC SPECT (Octreoscan) in the detection of NET manifestations.
Methods: Twenty-seven NET patients were prospectively examined.
Evaluation of positron emission tomography imaging using [68Ga]-DOTA-D Phe(1)-Tyr(3)-Octreotide in comparison to [111In]-DTPAOC SPECT. First results in patients with neuroendocrine tumors.
Mol Imaging Biol
November 2003
Department of Nuclear Medicine, University of Heidelberg, Heidelberg, Germany.
Purpose: [111In]-DTPAOC (Octreoscan(R)) has been shown to be very useful in the detection of somatostatin receptor (SSTR) positive tumors and their metastases using either conventional scintigraphy or single photon emission computed tomography (SPECT). The main drawback of this method is the limited spatial resolution and a somewhat low receptor affinity of the radiopeptide. Due to the increased spatial resolution and the ability of quantification, an agent for positron emission tomography (PET) imaging of SSTR is desirable.
View Article and Find Full Text PDF[Somatostatin receptor scintigraphy. When would a SPECT study be performed?].
Rev Esp Med Nucl
December 2003
Servicio de Medicina Nuclear, Hospital Clínico Universitario Lozano Blesa, Zaragoza.
Unlabelled: Somatostatin receptor scintigraphy has become an essential tool in the treatment planning of patients with carcinoid tumor (CaT) and pancreatic neuroendocrine tumors (PNET). However, the contribution of SPECT images in the diagnosis and staging of these tumors has not been well established.
Objective: 1) To find out if SPECT improves the sensitivity of planar imaging and adds any value to tumor diagnosis, and 2) To determine under which circumstances SPECT images must be obtained.
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