Vitis coignetiae Pulliat (Yamabudo) is used as a health juice and wine based on the abundant polyphenols and anthocyanins in its fruit. However, it is not known whether the leaves of this plant confer similar benefits. This study investigated the hepatoprotective effects of aqueous extracts from Vitis coignetiae Pulliat leaves (VCPL) in an animal model of nonalcoholic steatohepatitis (NASH). Rats were fed a choline-deficient high-fat diet for four weeks to generate fatty livers. NASH was induced by oxidative stress loading. Ten weeks later, blood and liver samples were collected from anesthetized animals and assessed biochemically, histologically, and histochemically to determine the extent of oxidative stress injury and the overall effects of VCPL. Six-week VCPL extract supplementation reduced serum levels of liver enzymes, decreased CYP2E1 induction, increased plasma antioxidant activities and delayed the progression of liver fibrosis. The findings suggested that VCPL has strong radical-scavenging activity and may be beneficial in preventing NASH progression.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.18926/AMO/31835 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Seed dispersal function of the brown bear Ursus arctos on Hokkaido Island in northern Japan: gut passage time, dispersal distance, germination, and effects of remaining pulp.
Oecologia
March 2024
Sapporo Maruyama Zoo, 3-1 Miyagaoka, Chuo-ku, Sapporo, Hokkaido, Japan.
Megafauna are important seed dispersers because they can disperse large quantities of seeds over long distances. In Hokkaido, Japan, the largest terrestrial animal is the brown bear (Ursus arctos) and other megafauna seed dispersers are lacking. Thus, brown bears are expected to have an important function as seed dispersers in Hokkaido.
View Article and Find Full Text PDFFirst report of Vitis cryptic virus (VCV) infecting mildew-resistant grapevine interspecific hybrids in France.
Plant Dis
October 2023
INRAE, 27057, UMR 1332 Biologie du Fruit et Pathologie, INRA - Université de Bordeaux, Paris, Aquitaine, France;
Article Synopsis
- - Vitis cryptic virus (VCV), discovered in Japan and found in China and Russia, is a deltapartitivirus that has unclear pathogenicity, though it’s generally considered non-pathogenic.
- - Recent studies reported unexpected symptoms like red blotch and leaf curl in hybrid plants from Bordeaux, prompting RNA sequencing to analyze the viral presence and identify various other viruses and viroids alongside VCV.
- - The RNA sequencing revealed two identical VCV RNA1 contigs and two VCV RNA2 contigs, showcasing high similarity to Japanese isolates, and all sequences were uploaded to GenBank for future reference.
The Endophytic Microbiome of Wild Grapevines Rupr. and Pulliat Growing in the Russian Far East.
Plants (Basel)
August 2023
Laboratory of Biotechnology, Federal Scientific Center of the East 27Asia Terrestrial Biodiversity, Far Eastern Branch of the Russian Academy of Sciences, 690022 Vladivostok, Russia.
Many grape endophytic microorganisms exhibit high potential for suppressing the development of grape diseases and stimulating grapevine growth and fitness, as well as beneficial properties of the crop. The microbiome of wild grapevines is a promising source of biocontrol agents, which can be beneficial for domesticated grapevines. Using next-generation sequencing (NGS) and classical microbiology techniques, we performed an analysis of bacterial and fungal endophytic communities of wild grapevines Rupr.
View Article and Find Full Text PDFFirst report of Vitis cryptic virus from grapevines in China.
Plant Dis
April 2022
xingcheng, China;
Vitis cryptic virus (VCV) was recently identified on wild Vitis coignetiae in Japan in 2021, and was tentatively classified as a new member of the genus Deltapartitivirus, which is consistent with the two-segmented genome encoding RdRp and CP (Nabeshima et al., 2021). In June 2020, a grapevine cv.
View Article and Find Full Text PDFAntimutagenic, anti-inflammatory, and antioxidative activities of the juice of Vitis ficifolia var. Ganebu, a woody vine in the grape family, known as Ryukyu-ganebu in Japan.
Genes Environ
November 2021
Faculty of Agriculture, University Farm, Kagawa University, 769-2304, Kagawa, Japan.
Background: Mutation, inflammation, and oxidative damage including lipid-peroxidation are factors involved in the development of cancer. We investigated the antimutagenic, in vivo and in vitro anti-inflammatory, and antioxidative effects of the juice of Vitis ficifolia var. ganebu (known as Ryukyu-ganebu in Japan) harvested in Kuchinoshima island (hereafter, the juice is referred to as ganebu-K) in comparison with the juice of Vitis coignetiae (crimson glory vine, known as yamabudo in Japan; hereafter, the juice is referred to as yamabudo) which we found antimutagenic and anti-inflammatory effects.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!