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SCAI blocks MAL-evolent effects on cancer cell invasion. | LitMetric

SCAI is a newly discovered protein that reduces cancer cell invasiveness. SCAI inhibits the MAL/SRF transcriptional activator complex that is downstream of Rho GTPase and actin, resulting in reduced expression of beta1-integrins and loss of invasive potential.

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Source
http://dx.doi.org/10.1038/ncb0509-540DOI Listing

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