Objective: To determine which rehydration method, oral or intravenous, parents would choose for their child when given the opportunity to make an informed decision and to determine factors influencing preference.
Methods: Parents of children, aged 6 months to 5 years, who presented to a pediatric emergency department with a chief complaint of vomiting and/or diarrhea were eligible. After triage evaluation and before physician assessment, research assistants presented educational materials regarding the method, risks, and benefits of both oral and intravenous rehydration. Parents were then asked to complete a survey asking them their preference, reasons for their preference, questions about their child's current illness, and demographic information.
Results: Two hundred sixty parents completed the study. Ninety eight (38%) preferred oral rehydration, and 162 (62%) preferred intravenous rehydration. Time of day, presence of siblings in the ED requiring parental attention, presence of another adult to provide support, parental age, educational attainment, and employment status were not statistically associated with the stated preference. Of those parents who selected intravenous rehydration, 53% stated that they would choose oral rehydration if there was an oral medication available that would significantly decrease vomiting. Of those parents who selected oral rehydration, 32% stated that they would choose intravenous rehydration if there was a topical medication available that would significantly decrease the pain of intravenous catheter placement.
Conclusions: When given the opportunity to make an informed decision, more parents chose intravenous rehydration. However, the prospect of an effective oral antiemetic medication might lead more parents to choose oral rehydration.
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http://dx.doi.org/10.1097/PEC.0b013e3181a34144 | DOI Listing |
J Invest Surg
December 2025
Department of Surgery, University of Minnesota Twin Cities Medical School, Minneapolis, MN, USA.
Background: Venous waveform analysis is an emerging technique to estimate intravascular fluid status by fast Fourier transform deconvolution. Fluid status has been shown proportional to , the amplitude of the fundamental frequency of the waveform's cardiac wave upon deconvolution. Using a porcine model of distributive shock and fluid resuscitation, we sought to determine the influence of norepinephrine on of the central venous waveform.
View Article and Find Full Text PDFJ Mol Histol
January 2025
Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 123 Dapi Rd. Niaosung Dist, Kaohsiung City, 83301, Taiwan.
This study tested whether combined ceftriaxone and adipose-derived mesenchymal stem cells (ADMSCs) would defend the spinal cord against acute spinal infection (ASI) in rodent. Adult-Male-SD rats were grouped into groups 1 (SC)/2 (ASI)/3 (ASI + ceftriaxone from days 2 to 28 after ASI induction)/4 (ASI + allogenic ADMSCs from day 2 for a total of 3 doses/3 consecutive intervals by intravenous injection)/5 (ASI + combined ceftriaxone and ADMSC) and spinal cord tissues were harvested by day 28. Circulatory levels of TNF-α/IL-6 at days 7 and 28, and these two parameters in spinal fluid at day 28 were lowest in group 1, highest in group 2, significantly lower in group 5 than in groups 3/4, and significantly lower in group 3 than in group 4 (all p < 0.
View Article and Find Full Text PDFHeliyon
December 2024
Department of Critical Care Medicine, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen, 518020, China.
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View Article and Find Full Text PDFOpen Forum Infect Dis
January 2025
Medicine Department, Providence St Joseph Hospital, Orange, California, USA.
is a rapidly emerging fungal pathogen associated with high resistance rates, particularly in healthcare settings. It most commonly affects patients with severe underlying medical conditions and requiring complex medical care. Patients with invasive medical devices tend to be at increased risk for getting and developing infection.
View Article and Find Full Text PDFA variety of autoimmune disorders are associated with an increased risk of thrombosis. Previous studies have suggested combined therapy of heparin and therapeutic plasma exchange (TPE) with fresh frozen plasma (FFP) as the replacement fluid is beneficial in some cases of acute flare-up of autoimmune diseases complicated by thrombotic events. Nevertheless, it remains unknown whether clinicians do more harm than good by exposing patients to a "thrombotic storm" through simultaneous administration of heparin and the clotting factors in the FFP during TPE.
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