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Near-fatal cocaine intoxication in an infant with thrombotic microangiopathy associated with multiple organ failure.
Rev Paul Pediatr
August 2023
Hospital Clínico Dra. Eloísa Díaz I., Pediatric Critical Care Unit, Santiago, Chile.
Objective: To report a pediatric case of drug-induced thrombotic microangiopathy caused by cocaine.
Case Description: We report a nine-month-old patient who developed thrombotic microangiopathies after extreme cocaine intoxication, multiple organ dysfunction syndrome with hemodynamic dysfunction, anuric renal failure, liver failure, encephalopathy, and myocardial injury, corresponding phenotypically to thrombocytopenia-associated multiple organ failure. The patient received continuous venous hemofiltration and therapeutic plasma exchange, recovering satisfactorily.
Critical asthma syndrome in trauma patients - A case report and literature review.
Trauma Case Rep
December 2022
University of Nevada, Las Vegas, Department of Internal Medicine, 1707 W Charleston Blvd Suite 100, Las Vegas, NV 89102, United States of America.
Critical asthma syndrome (CAS) is an umbrella term for many acute, life-threatening, and treatment resistant variants of asthma exacerbation, including refractory asthma, near fatal asthma, and status asthmaticus. The asthma mortality rate has steadily increased through the last decade and disproportionately affects women, African-Americans, patients of low socioeconomic status, and adults over the age of 55. Increased awareness of the diagnosis and therapies for CAS can help establish a therapeutic strategy for asthma beyond corticosteroids, bronchodilators, and other conventional treatments.
View Article and Find Full Text PDFRadiocontrast-Diatrozate and Iopromide-Induced Severe Hypocalcemia Leading to Painful Tetanic and Severe Laryngeal Spasm: A Near Fatal Encounter.
Cureus
July 2022
Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, IND.
Routinely advised radiological investigations like contrast-enhanced scans can have adverse effects on electrolyte imbalance due to the administration of Radiocontrast. Urograffin (Diatrizoate) and Ultravist (Iopromide) are some of the common examples of contrasts given to patients that possibly led to chelation of the calcium in serum causing severe carpopedal spasms and painful muscular tetany in our patient. Here we report a case of a 32-year-old female patient with acute gastroenteritis who presented with complaints of pain in the abdomen, multiple episodes of vomiting, and loose stools underwent contrast-enhanced computed tomography (CECT) scan of the abdomen, and developed severe painful muscular tetanic spasms after intravenous and oral contrast was administered.
View Article and Find Full Text PDFSpontaneous Near Fatal Hemorrhage into Neurofibromatosis Type 1 Lesion in the Scalp.
Oman Med J
May 2022
Vascular Surgery Unit, Department of Surgery, Sultan Qaboos University Hospital, Muscat, Oman.
Neurofibromatosis type 1 (NF1) (von Recklinghausen's disease) is an autosomal dominant disorder characterized by café-au-lait spots, pigmented hamartomas of the iris, and multiple neurofibromas. Patients can present with hemorrhage secondary to trauma or rarely with spontaneous hemorrhage, both of which can be lethal and life-threatening. We report a 14-year-old girl with a rapidly expanding hematoma in a rare presentation of spontaneous bleed into the NF1 lesion in her scalp.
View Article and Find Full Text PDFCurrent Development of Minimally Invasive Repair of Pectus Excavatum (MIRPE).
Children (Basel)
March 2022
Department of Pediatric Surgery, Children's Hospital of Eastern Switzerland, CH-9006 St. Gallen, Switzerland.
For decades, open surgical repair was the only available method to treat congenital and acquired chest wall deformities (CWDs). In 1998, D. Nuss described a minimally invasive procedure for surgical repair of Pectus excavatum (PE).
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