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Fluoride Induces Toxic Effects on the A549 Pulmonary Cell Line at Non-cytotoxic Concentrations.
Biol Trace Elem Res
January 2025
Departamento de Toxicología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, AvInstituto Politécnico Nacional 2508, Col San Pedro ZacatencoCDMX, C.P. 07360, Mexico City, Mexico.
Fluoride is emitted into the air not only through gas emissions but also from volcanic ash, leading to contact via inhalation. Therefore, the objective of the present study was to evaluate the cellular and biochemical responses in the A549 cell line after exposure to NaF (sodium fluoride) concentrations lower than those previously used in other studies to determine the impact on the lung epithelium. A549 cells were exposed to different concentrations (0.
View Article and Find Full Text PDFApplication of integrated omics in aseptic loosening of prostheses after hip replacement.
Mol Med Rep
March 2025
Department of Orthopedics, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.
Aseptic loosening (AL) of artificial hip joints is the most common complication following hip replacement surgery. A total of eight patients diagnosed with AL following total hip arthroplasty (THA) undergoing total hip replacement and eight control patients diagnosed with avascular necrosis of femoral head (ANFH) or femoral neck fracture undergoing THA were enrolled. The samples of the AL group were from synovial tissue surrounding the lining/head/neck of the prosthesis, and the samples of the control group were from the synovium in the joint cavity.
View Article and Find Full Text PDFCharacterization of the E26H Mutant Schistosoma japonicum Glutathione S-Transferase.
Proteins
January 2025
Laboratory of Retroviral Biochemistry, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Glutathione-S-transferase, such as that of Schistosoma japonicum (sjGST) belongs to the most widely utilized fusion tags in the recombinant protein technology. The E26H mutation of sjGST has already been found to remarkably improve its ability for binding divalent ions, enabling its purification with immobilized metal affinity chromatography (IMAC). Nevertheless, most characteristics of this mutant remained unexplored to date.
View Article and Find Full Text PDFThe influence of ammonia-N and salinity levels on oxidative stress markers, hepatic enzymes, and acid phosphatase activity in Nile tilapia (Oreochromis niloticus).
Sci Rep
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Department of Fisheries, Faculty of Natural Resources, Isfahan University of Technology, Isfahan, 84156-8311, Iran.
The point of our study was to examine the interaction of ammonia-N poisoning and salinity on serum enzymes and oxidative stress factors of blood and liver in Nile tilapia (Oreochromis niloticus). The 50% lethal concentration (LC) in 96 h was 0.86 mg/L of ammonia-N.
View Article and Find Full Text PDFEffect of isolated compounds from Combretum trifoliatum on toxicity and detoxification enzymes in Nilaparvata lugens.
Sci Rep
January 2025
Animal Toxicology and Physiology Speciality Research Unit, Zoology Department, Faculty of Science, Kasetsart University, Bangkok, 10900, Thailand.
The brown planthopper (BPH) Nilaparvata lugens (Stål) is a major insect pest of Oryza sativa that causes crop yield loss in tropical regions, including Thailand. In this study, the crude ethanolic extract of the leaves and branches of Combretum trifoliatum , its active isolated components, apigenin and camphor, and Finopril were tested for their ability to control the first to fifth instars of N. lugens.
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