The levels of soluble CD95 (sCD95) antigen and CD95+ mononuclear cells were studied in the peripheral blood, induced sputum (IS), expired air condensate (EAC) of patients with chronic obstructive pulmonary disease (COPD). There was an increase in the relative count of CD95+ mononuclear cells and a reduction in the level of sCD95 antigen in the peripheral blood of patients with severe COPD. The elevated levels of sCD95 antigen and CD95+ mononuclear cells were revealed in IS and EAC in moderate COPD.

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