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Giant cell arteritis (GCA), a systemic vasculitis affecting large and medium-sized arteries, poses significant diagnostic and management challenges, particularly in preventing irreversible complications like vision loss. Recent advancements in artificial intelligence (AI) technologies, including machine learning (ML) and deep learning (DL), offer promising solutions to enhance diagnostic accuracy and optimize treatment strategies for GCA. This systematic review, conducted according to the PRISMA 2020 guidelines, synthesizes existing literature on AI applications in GCA care, with a focus on diagnostic accuracy, treatment outcomes, and predictive modeling.
View Article and Find Full Text PDFNovel compound heterozygous mutations in the LARS2 gene in a Chinese family with hearing loss.
Neurogenetics
January 2025
Department of Otolaryngology & Head and Neck, Liuzhou Worker's Hospital of Guangxi Zhuang Autonomous Region, 156 Heping Road, Liuzhou, 545007, China.
Background: Mutations in the LARS2 gene are correlated with Perrault syndrome, a rare autosomal recessive genetic disorder, that is typically characterized by sensorineural hearing loss and ovarian insufficiency.
Methods: Whole-exome sequencing and mutational analysis were employed to identify hearing loss-causing genes in a Chinese family from the Guangxi Zhuang Autonomous Region. Clinical phenotypes, audiological data, and color Doppler ultrasound of the family were collected, and a series of computer software were used to analyze the impact of genetic variations on protein structure and function.
The usefulness of color Doppler images using epicardial echocardiography for diagnosis of coronary artery ostial stenosis in an infant.
J Echocardiogr
January 2025
Department of Pediatric Cardiology, Chukyo Hospital, 1-1-10 Sanjo, Minami-ku, Nagoya, Aichi, Japan.
Perioperative ultrasound screening of lower extremity veins is effective in the prevention of fatal pulmonary embolism in orthopedic patients.
Sci Rep
January 2025
Department of Orthopedics and Traumatology, Honghui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China.
Patients at high risk of deep vein thrombosis are recommended to undergo lower-extremity ultrasonography to screen for pulmonary embolism (PE); however, there are few reports on whether this can effectively reduce the occurrence of fatal pulmonary embolism (FPE). This study aimed to assess the risk factors associated with PE and to investigate whether perioperative ultrasound screening of lower extremity veins in orthopedic patients can effectively reduce the incidence of FPE. We enrolled 137 patients with PE who underwent orthopedic surgery between 2013 and 2020.
View Article and Find Full Text PDFSurgical technique for mitral valve repair in dogs using a novel method to anchor artificial chordae tendineae with emphasis on key intraoperative decision points.
Front Vet Sci
December 2024
Department of Cardiology, Uenonomori Animal Hospital, Tokyo, Japan.
Objectives: Surgical options for mitral valve repair in dogs are unstandardized and influenced by various factors. This study describes a four-point surgical technique (MI-4) to reduce mitral regurgitation and provides data from a study of dogs with 12 months of follow up.
Methods: Twenty-five dogs with stages C or D mitral insufficiency were treated by one of two surgeons using the MI-4 procedure at Ueno no Mori Animal Hospital between October 2021 and May 2023.
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