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spp. Infection in Adult Kidney Transplant Patients: A Systematic Review and Meta-Analysis.
J Clin Med
October 2024
Clinic of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.
Diarrhea frequently occurs after vascular organ transplantation, including kidney transplants. This may result from non-infectious factors, adverse effects of immunosuppressive medications, or infections caused by various pathogens, including viruses, bacteria, fungi, or parasites, for example, intestinal protozoan parasites such as spp., which are particularly dangerous for immunocompromised patients.
View Article and Find Full Text PDFMagnetic Resonance Cholangiopancreatography (MRCP) Findings in a Patient With AIDS Cholangiopathy and Cryptosporidiosis.
Cureus
September 2023
Diagnostic Radiology and Molecular Imaging, Corewell Health William Beaumont University Hospital, Royal Oak, USA.
AIDS cholangiopathy is a rare condition characterized by intra- and extra-hepatic ductal strictures causing biliary obstruction primarily in individuals with advanced HIV infection and low clusters of differentiation 4 (CD4) count. This case report presents a male patient with a history of HIV, poor adherence to antiretroviral therapy (ART), and chronic cryptosporidiosis infection, who exhibited clinical and radiological findings consistent with advanced immunocompromise and AIDS cholangiopathy. The patient presented with respiratory symptoms, weight loss, renal dysfunction, and elevated liver enzymes.
View Article and Find Full Text PDFVariants Disrupting CD40L Transmembrane Domain and Atypical X-Linked Hyper-IgM Syndrome: A Case Report With Leishmaniasis and Review of the Literature.
Front Immunol
May 2022
Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
X-linked hyper-IgM (XHIGM) syndrome is caused by mutations of the CD40LG gene, encoding the CD40L protein. The clinical presentation is characterized by early-onset infections, with profound hypogammaglobulinemia and often elevated IgM, susceptibility to opportunistic infections, such as pneumonia, biliary tract disease due to , and malignancy. We report a 41-year-old male presenting with recurrent leishmaniasis, hypogammaglobulinemia, and myopathy.
View Article and Find Full Text PDFPotential therapeutic and prophylactic effects of Asafoetida in murine cryptosporidiosis.
J Parasit Dis
September 2020
Department of Parasitology, Theodor Bilharz Research Institute, Giza, Egypt.
is an important coccidian parasite that could infect the intestine, respiratory and biliary tracts of man and animals. This study aims to test the potential therapeutic and prophylactic effects of a natural herbal agent (Asafoetida) versus the nowadays drug of choice (Nitazoxanide). Fifty bred female, white Albino mice of CDI strain were divided into 5 groups; : immunosuppressed, infected with and treated with Asafoetida, : immunosuppressed, prophylactically treated with Asafoetida for 7 days prior to infection, : immunosuppressed, infected and treated with Nitazoxanide, : immunosuppressed and infected (Positive control), : immunosuppressed and non infected (Negative control).
View Article and Find Full Text PDFComplications of Cryptosporidium infection after pediatric liver transplantation: Diarrhea, rejection, and biliary disease.
Pediatr Transplant
December 2020
Division of Pediatric Surgery, Children's Mercy Hospital, Kansas City, Missouri, USA.
Background: Cryptosporidium enteritis can be devastating in the immunocompromised host. In pediatric liver transplant recipients, infection may be complicated by prolonged carriage of the parasite, rejection, and biliary tree damage and fibrosis. Herein, we report on six patients and their long-term outcomes following cryptosporidiosis.
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