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Crosstalk between gut-brain axis: unveiling the mysteries of gut ROS in progression of Parkinson's disease.
Inflammopharmacology
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Department of Pharmacology, Central University of Punjab, Ghudda, Bathinda, 151401, Punjab, India.
"Path to a good mood lies through the gut." This statement seems to imply that it has long been believed that the gut is connected with the brain. Research has shown that eating food activates the reward system and releases dopamine (DA), establishing a link between the peripheral and central nervous system.
View Article and Find Full Text PDFGenome-wide association study identifies 30 obsessive-compulsive disorder associated loci.
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Department of Community Health and Epidemiology and Faculty of Computer Science, Dalhousie University, Halifax, NS, Canada.
Article Synopsis
- Obsessive-compulsive disorder (OCD) affects about 1% of people and has a strong genetic component, but previous studies have not fully explained its genetic causes or biological mechanisms.
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Organizational change is a key mechanism to ensure the sustainability of healthcare systems. However, healthcare organizations are persistently difficult to change, and literature is riddled with examples of failed change endeavors. In this chapter, we attempt to unravel the underlying causes for failed organizational change.
View Article and Find Full Text PDFLipoprotein(a): Solving the Puzzle, Deciphering the Riddle, Unraveling the Enigma.
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Department of Medicine, McGill University, McGill University Health Center, Montreal, Quebec, Canada. Electronic address:
Whilst widespread in the microbial world, the hybrid cluster protein (HCP) has been paradoxically a long-time riddle for microbiologists. During three decades, numerous studies on a few model organisms unravelled its structure and dissected its metal-containing catalyst, but the physiological function of the enzyme remained elusive. Recent studies on bacteria point towards a nitric oxide reductase activity involved in resistance during nitrate and nitrite reduction as well as host infection.
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