The surface structure of a xanthine stone from a patient with hereditary xanthinuria was examined using scanning electron microscopy. This revealed that the xanthine stone was composed of at least two very different structures. One was a spherical protrusion with craters and a fine granular surface and the other consisted of a granular growth of plate-like crystals.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1007/BF02549601 | DOI Listing |
J Inflamm Res
January 2025
Department of Internal Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, People's Republic of China.
Purpose: Serum uric acid (SUA) is primarily produced through the hydrolysis of purines in the liver, with its excretion largely handled by the kidneys. Urate transporter 1 (URAT1) inhibitors are known to enhance uric acid elimination via the kidneys, but they also increase the risk of kidney stone formation. Currently, xanthine oxidase (XO) inhibitors are the predominant uric-lowering medications on the market.
View Article and Find Full Text PDFArch Ital Urol Androl
November 2024
C.d.C. Ambrosiana, Cesano Boscone, Milan.
Theobromine (or 3,7-dimethylxanthine) is a natural alkaloid present in cocoa plant and its derivatives, such as chocolate. About 20% of ingested theobromine is excreted unchanged in the urine. Theobromine also derived from caffeine that is metabolized into theobromine by 12%.
View Article and Find Full Text PDFArch Esp Urol
November 2024
Department of Urology, Affiliated Hospital of Qingdao University, 266000 Qingdao, Shandong, China.
Sci Rep
December 2024
Department of Urology, Qinghai University Affiliated Hospital, Xining, 810000, China.
Anal Methods
January 2025
Research Center of Jiangxi Province for Engineering Technology of Calculus Prevention and Control, Gannan Medical University, Ganzhou 341000, P. R. China.
Accurate determination of elemental concentrations in uric acid (UA) stones is crucial for understanding their formation process. However, the lack of matrix-matched calibration standards has limited the application of laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) in this field. This study addresses this limitation by preparing a synthetic UA precipitate (UA-1) doped with 17 elements using a recrystallization method.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!