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The First Patient with Tinea Manuum because of Isolated in Malta.
Skinmed
January 2025
Department of Dermatology, Mater Dei Hospital, Msida, Malta.
A 39-year-old woman presented to the dermatology department in January 2022 with a 3-week history of a progressively enlarging and intensely pruritic erythematous annular nodule on her left hand. The lesion started as a small blister, which was initially presumed to be a flare up of her pompholyx dermatitis. On her physician's advice, she applied clobetasol propionate ointment twice daily for 5 days; however the blister continued to increase in size until it burst, revealing raw inflamed skin.
View Article and Find Full Text PDFSequential occurrence of primary cutaneous indeterminate cell histiocytosis after oesophageal cancer and subsequent bullous pemphigoid: a case report.
Br J Hosp Med (Lond)
July 2024
Department of Dermatology, Zhejiang Provincial Hospital of Dermatology, Huzhou, Zhejiang, China.
Indeterminate cell histiocytosis is a rare proliferative histiocytic disease with an unknown aetiology, which shares immunophenotypic features of both Langerhans cells and macrophages. There is a relationship between indeterminate cell histiocytosis and cancer, while there are no reports about indeterminate cell histiocytosis and bullous pemphigoid. In this study, we reported the rare case of a patient with primary cutaneous indeterminate cell histiocytosis who had been diagnosed with oesophagal cancer and later developed bullous pemphigoid.
View Article and Find Full Text PDFPemphigus Herpetiformis: A Report of an Unusual Type of Pemphigus in a Three-Year-Old Female.
Cureus
April 2024
Dermatology, As'ad Al-Hamad Dermatological Center, Kuwait City, KWT.
Article Synopsis
- - Pemphigus herpetiformis (PH) is a rare autoimmune skin condition that mostly affects adults, but it's extremely uncommon in young children, like the three-year-old girl in the case study.
- - The child exhibited skin issues resembling other conditions, and a biopsy revealed several specific features, including inflammation and blisters.
- - Treatment with clobetasol ointment and dapsone led to significant improvement in her symptoms, highlighting the need to recognize PH in pediatric cases and encouraging more research to understand it better.
A case of IgA pemphigus, with a poor response to dapsone, successfully treated with adalimumab.
Clin Case Rep
May 2024
Department of Dermatology, Razi Hospital Tehran University of Medical Sciences (TUMS) Tehran Iran.
Article Synopsis
- * The condition is characterized by itchy, blistering skin lesions, primarily affecting areas like the axilla and groin, due to IgA autoantibodies disrupting cell adhesion in the skin.
- * The study presents a case where a 50-year-old male with severe IgA pemphigus had a poor response to Dapsone but was successfully treated with an injection of the TNFa inhibitor, adalimumab.
Linear IgA bullous dermatosis associated with immunotherapy.
Dermatol Online J
December 2023
Long School of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Article Synopsis
- Linear IgA bullous dermatosis (LABD) is a rare autoimmune skin condition characterized by blisters caused by IgA autoantibodies, and can resemble bullous pemphigoid (BP), which is due to IgG and IgE autoantibodies.
- A case study of a 67-year-old woman with metastatic ovarian cancer showed new blistering skin lesions after she started immunotherapy, which were diagnosed as LABD based on skin biopsy results.
- The patient’s condition did not improve with prednisone but significantly healed after starting dapsone, emphasizing the need for accurate diagnosis through histology and immunofluorescence to guide effective treatment without halting immunotherapy.
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