[Isolation and identification of compounds from marine mangrove plant Avicennia marina].

Beijing Da Xue Xue Bao Yi Xue Ban

State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.

Published: April 2009

Objective: To investigate the chemical constituents from Avicennia marina.

Methods: The isolation and purification of the CH2Cl2 and n-BuOH fractions of this plant were performed, and the chemical structures were elucidated by spectral analysis as well as comparison of their spectral data with literature values.

Results: Three novel compounds were obtained and identified as erythro-guaiacylglycerol-beta-ferulic acid ether (1), marinnone A (16) and marinnone B (17), along with eighteen known compounds as threo-guaiacylglycerol-beta-ferulic acid ether (2), eleutheroside E2 (3), (+)-lirioresinol A (4), dihydroxymethyl-bis (3, 5-dimethoxy-4-hydroxyphenyl) tetrahydrofuran-9-O-beta-glucopyranoside (5), (+)-lyoniresinol 3a-O-beta-D-glucopyranoside (6), (-)-lyoniresinol 3a-O-beta-D-glucopyranoside (7), epi-pinoresinol (8), leucoseceptoside A (9), jionoside C (10), salsaside A (11), ilicifolioside A (12), acteoside (13), isoacteoside (14), ethyl ferulate (15), avicennone D (18), avicenone E (19), avicennol C (20), and stenocarpoquinone B (21).

Conclusion: Three new compounds (1, 16 and 17) were obtained and thirteen known compounds, 2-12, 14 and 15 were isolated from Avicennia genus for the first time.

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