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Enhancing Environmental and Human Health Management Through the Integration of Advanced Revitalization Technologies Utilizing Artificial Intelligence.
Toxics
November 2024
The Dean's Office, Defense and Security University "Dr. Franjo Tuđman", 10000 Zagreb, Croatia.
Pollution can be broadly defined as the presence of contaminants or energy sources detrimental to ecosystems and human health. The human organism serves as a valuable indicator of ecosystem contamination. However, understanding physiological disorders and correlating specific contaminants with disease development is a complex and arduous task, necessitating extensive scientific research spanning years or even decades.
View Article and Find Full Text PDFExploring Potential Impact of Graphene Oxide and Graphene Oxide-Polyethylenimine on Biological Behavior of Human Amniotic Fluid-Derived Stem Cells.
Int J Mol Sci
December 2024
Cell Reprogramming and Differentiation Lab, "G. d'Annunzio University" of Chieti-Pescara, 66100 Chieti, Italy.
Regenerative medicine and tissue engineering aim to restore or replace impaired organs and tissues using cell transplantation supported by scaffolds. Recently scientists are focusing on developing new biomaterials that optimize cellular attachment, migration, proliferation, and differentiation. Nanoparticles, such as graphene oxide (GO), have emerged as versatile materials due to their high surface-to-volume ratio and unique chemical properties, such as electrical conductivity and flexibility.
View Article and Find Full Text PDFBulgarian Experience in Vaginal Electronic Brachytherapy for Gynecologic Cancers' Treatment-First Results.
J Clin Med
December 2024
Scientific and Innovative Program Med for Health, Medical University Pleven, 1, Saint Kliment Ohridski Street, 5800 Pleven, Bulgaria.
: The objective of this study is to prospectively collect dosimetric and clinical data on vaginal cuff electronic brachytherapy and propose a protocol for the procedure. Twenty-five patients who had proven endometrial or cervical carcinoma and had undergone radical hysterectomy have been treated with vaginal cuff electronic brachytherapy. Treatment session durations and doses to the targets and the organs at risk have been extracted from the treatment planning software.
View Article and Find Full Text PDFThe Chemokine System as a Key Regulator of Pulmonary Fibrosis: Converging Pathways in Human Idiopathic Pulmonary Fibrosis (IPF) and the Bleomycin-Induced Lung Fibrosis Model in Mice.
Cells
December 2024
Laboratory of Immuno-Neuro Modulation (INEM), UMR7355 Centre National de la Recherche Scientifique (CNRS), University of Orleans, 45071 Orleans, France.
Idiopathic pulmonary fibrosis (IPF) is a chronic and lethal interstitial lung disease (ILD) of unknown origin, characterized by limited treatment efficacy and a fibroproliferative nature. It is marked by excessive extracellular matrix deposition in the pulmonary parenchyma, leading to progressive lung volume decline and impaired gas exchange. The chemokine system, a network of proteins involved in cellular communication with diverse biological functions, plays a crucial role in various respiratory diseases.
View Article and Find Full Text PDFImpact of Deep Learning-Based Image Reconstruction on Tumor Visibility and Diagnostic Confidence in Computed Tomography.
Bioengineering (Basel)
December 2024
Department of Radiology, Jena University Hospital, Friedrich Schiller University, 07747 Jena, Germany.
Deep learning image reconstruction (DLIR) has shown potential to enhance computed tomography (CT) image quality, but its impact on tumor visibility and adoption among radiologists with varying experience levels remains unclear. This study compared the performance of two deep learning-based image reconstruction methods, DLIR and Pixelshine, an adaptive statistical iterative reconstruction-volume (ASIR-V) method, and filtered back projection (FBP) across 33 contrast-enhanced CT staging examinations, evaluated by 20-24 radiologists. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were measured for tumor and surrounding organ tissues across DLIR (Low, Medium, High), Pixelshine (Soft, Ultrasoft), ASIR-V (30-100%), and FBP.
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