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Human Hair Follicle Mesenchymal Stem Cell-Derived Exosomes Attenuate UVB-Induced Photoaging via the miR-125b-5p/TGF-β1/Smad Axis.
Biomater Res
January 2025
Center for Plastic & Reconstructive Surgery, Department of Dermatology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang, China.
Cutaneous photoaging, induced by chronic exposure to ultraviolet (UV) radiation, typically manifests as alterations in both the physical appearance and functional properties of the skin and may predispose individuals to cancer development. Recent studies have demonstrated the reparative potential of exosomes derived from mesenchymal stem cells in addressing skin damage, while specific reports highlight their efficacy in ameliorating skin photoaging. However, the precise role of exosomes derived from human hair follicle mesenchymal stem cells (HFMSC-Exos) in the context of cutaneous photoaging remains largely unexplored.
View Article and Find Full Text PDFEnhanced post-thaw functional characteristics of cryopreserved caprine dermal fibroblasts through adhesion to extracellular matrix proteins.
Mol Biol Rep
January 2025
Goat Genetics and Breeding Division, ICAR-Central Institute for Research On Goats, Makhdoom, Farah, Mathura, 281 122, Uttar Pradesh, India.
Background: Extracellular matrix (ECM) proteins play a crucial role in regulating the biological properties of adherent cells. For cryopreserved fibroblasts, a favourable ECM environment can help restore their natural morphology and function more rapidly, minimizing post-thaw stress responses.
Methods And Results: This study explored the functional responses of cryopreserved enriched caprine adult dermal fibroblast (cadFibroblast) cells to structural [collagen-IV and rat tail collagen (RTC)] and adhesion ECM proteins (laminin, fibronectin, and vitronectin) under in vitro culture conditions.
Enhancing Corneal Sensitivity in Diabetic Patients Through an Innovative Ophthalmic Solution: In Vivo and Vitro Results.
J Clin Med
January 2025
Department of Sciences, Section of Biomedical Sciences and Technologies, Roma Tre University, Viale Marconi 446, 00146 Rome, Italy.
: Diabetes is a well-recognised factor inducing a plethora of corneal alterations ranging from dry eye to reduced corneal sensibility, epithelial defects, and reduced cicatrisation. This cohort study aimed to assess the efficacy of a novel ophthalmic solution combining cross-linked hyaluronic acid (CHA), chondroitin sulfate (CS), and inositol (INS) in managing diabetes-induced corneal alterations. Specifically, it evaluated the solution's impact on the tear breakup time (TBUT), the ocular surface disease index (OSDI), and corneal sensitivity after three months of treatment.
View Article and Find Full Text PDFEvaluation of Four Methods to Determine the Degree of Cure of Melamine-Based Direct Pressed Laminates on Particleboards: Two Improved UV Absorption Methods, the Kiton Test, and Near Infrared Spectroscopy.
Materials (Basel)
December 2024
Fraunhofer WKI, 38108 Braunschweig, Germany.
Despite its importance, the determination of the degree of cure of melamine-based laminates often relies on tests with limited accuracy and validity. Undercured surfaces may suffer insufficient resistance to scratching and heat as well as substandard surface quality. Overcured melamine surfaces tend to crack and entail the inefficient utilization of the press-the panels could have been pressed for a shorter time.
View Article and Find Full Text PDFEffect of mechanical instrumentation on titanium implant surface properties.
Dent Mater
January 2025
Department of Materials, School of Natural Sciences, University of Manchester, Manchester M13 9PL, UK; Photon Science Institute, University of Manchester, Manchester M13 9PL, UK. Electronic address:
Objective: To assess the impact of mechanical decontamination using rotary brushes on the surface topography, elemental composition, roughness, and wettability of titanium implant surfaces.
Methods: Four commercially available rotary brushes were used: Labrida BioClean Brush® (LB), i-Brush1 (IB), NiTiBrush Nano (NiTiB), and Peri-implantitis Brush (PIB). Seventy-five titanium discs with sandblasted, large-grit, acid-etched (SLA) surfaces were randomly assigned to five groups (n = 15): LB, IB, NiTiB, PIB, and a control group.
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