Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1089/zeb.2009.9998 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Extractable organic matter from PM inhibits cardiomyocyte differentiation via AHR-mediated mA RNA methylation.
J Hazard Mater
January 2025
The First Affiliated Hospital, MOE Education Key Laboratory of Geriatric Diseases and Immunology, Suzhou Medical College of Soochow University, Suzhou, China; Jiangsu Key Laboratory of Preventive and Translational Medicine for Major Chronic Non-Communicable Diseases, China. Electronic address:
An ever-increasing body of research has established a link between maternal PM2.5 exposure and congenital heart diseases in the offspring, but the underlying mechanisms remain elusive. We recently reported that activation of the aryl hydrocarbon receptor (AHR) by PM2.
View Article and Find Full Text PDFFoxm1 promotes differentiation of neural progenitors in the zebrafish inner ear.
Dev Biol
January 2025
Biology Department, Texas A&M University, College Station, TX, 7843-3258, USA. Electronic address:
During development of the vertebrate inner ear, sensory epithelia and neurons of the statoacoustic ganglion (SAG) arise from lineage-restricted progenitors that proliferate extensively before differentiating into mature post-mitotic cell types. Development of progenitors is regulated by Fgf, Wnt and Notch signaling, but how these pathways are coordinated to achieve an optimal balance of proliferation and differentiation is not well understood. Here we investigate the role in zebrafish of Foxm1, a transcription factor commonly associated with proliferation in developing tissues and tumors.
View Article and Find Full Text PDFTetrachlorantraniliprole induces neurodevelopmental toxicity through oxidative stress-mediated apoptosis and dysregulation of Wnt signaling pathway.
Aquat Toxicol
December 2024
School of Life Science, Nanchang University, Nanchang 330031, China; Chongqing Research Institute of Nanchang University, 402660, China. Electronic address:
Tetrachlorantraniliprole (TCTP) is a novel bisamide insecticide and widely used to protect against lepidopteran insect species. However, the application of TCTP in rice fields often leads to water pollution, posing threats to aquatic organisms and potentially to human health. Few studies have assessed the toxic effects of TCTP on aquatic animals.
View Article and Find Full Text PDFRANKL regulates differentially breast cancer stem cell properties through its RANK and LGR4 receptors.
Biochim Biophys Acta Mol Cell Res
December 2024
Innovation and Precision Medicine Laboratory, Instituto Nacional de Medicina Genómica, Periférico Sur No.4809, Col Arenal Tepepan, Tlalpan, Mexico City C.P. 14610, Mexico. Electronic address:
Background: Breast cancer stem cells (BCSC) are a subpopulation responsible for cancer resistance and relapse. The receptor activator of nuclear factor kappa-Β ligand (RANKL) is a cytokine capable of activating RANK and LGR4 receptors. RANKL/RANK signaling maintains the self-renewal of BCSCs, however, the effect of RANKL via LGR4 remains unclear.
View Article and Find Full Text PDFAnalysis of a shark reveals ancient, Wnt-dependent, habenular asymmetries in vertebrates.
Nat Commun
November 2024
CNRS, Sorbonne Université, UMR7232-Biologie Intégrative des Organismes Marins, Observatoire Océanologique, Banyuls-sur-Mer, France.
The mode of evolution of left-right asymmetries in the vertebrate habenulae remains largely unknown. Using a transcriptomic approach, we show that in a cartilaginous fish, the catshark Scyliorhinus canicula, habenulae exhibit marked asymmetries, in both their medial and lateral components. Comparisons across vertebrates suggest that those identified in lateral habenulae reflect an ancestral gnathostome trait, partially conserved in lampreys, and independently lost in tetrapods and neopterygians.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!