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Flow-Through Flaps as a Robust Method for Advanced Free Flap Reconstruction in the Head and Neck: A Multi-Institutional Experience.
Head Neck
January 2025
Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Background: Flow-through flaps (FTFs) are an advanced technique in which a free flap is anastomosed to the pedicle of another free flap to reconstruct extensive head and neck defects when recipient vessels are scarce.
Methods: A multi-institutional cohort of FTFs used for head and neck reconstruction were reviewed. For comparison, FTF outcomes were compared to free flaps that required vein grafts (VG) to reach distant recipient vessels.
Publication of Medical Student Summer Research: A Multi-institutional Analysis.
Med Sci Educ
December 2024
Department of Academic Affairs, Brody School of Medicine at East, Carolina University, Greenville, NC USA.
Objective: Summer research programs can support medical students' exposure to research and scholarly activity, and strengthen their applications for residency positions, particularly if students are able to generate peer-reviewed publications resulting from their summer experience. We aimed to estimate the rate of publication among medical student summer projects and identify any predictors of projects' progress to publication.
Methods: Projects were identified from abstract books published by five medical schools' summer research programs for rising second-year medical students.
Unveiling Inequities: Racial Disparities in Risk-Reducing Mastectomy for Breast Cancer Prevention.
Clin Breast Cancer
December 2024
Division of Plastic Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT. Electronic address:
Background: Risk-reducing mastectomy (RRM) significantly lowers breast cancer risk as a preventive surgery. While racial disparities in breast cancer treatment are well-documented, research on racial differences in the utilization and outcomes of RRM is limited.
Methods: We retrospectively analyzed the American College of Surgeons National Surgical Quality Improvement Program (2008-2022) to identify women who underwent RRM.
Perioperative Changes in Serum Transaminases Levels Predicts Long-Term Survival Following Liver Resection of Hepatocellular Carcinoma.
Ann Surg Oncol
December 2024
Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH, USA.
Background: We sought to define whether and how hepatic ischemia/reperfusion (I/R) as manifested by perioperative aspartate aminotransferase (AST) and alanine aminotransaminase (ALT) levels impact long-term outcomes after curative-intent resection of hepatocellular carcinoma (HCC).
Patients And Methods: Intrasplenic injection of HCC cells was used to establish a murine model of HCC recurrence with versus without I/R injury. Patients who underwent curative resection for HCC were identified from a multi-institutional derivative cohort (DC) and separate external validation (VC) cohort.
Introduction: Adjuvant pembrolizumab versus placebo significantly improved disease-free survival (DFS) in renal cell carcinoma (RCC) patients at high risk of recurrence following nephrectomy in KEYNOTE-564 trial (NCT03142334). The objective of this study was to evaluate efficacy and safety of adjuvant pembrolizumab in a real-world setting.
Methods: In this multicenter retrospective study, RCC patients receiving adjuvant pembrolizumab between 01/22 and 10/23 at seven tertiary referral centers were included.
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