AI Article Synopsis

  • The study investigated erythropoietin levels in the blood and its expression in the exocervical epithelium of reproductive-aged women with normal red blood cell counts.
  • Findings revealed that erythropoietin expression in the cervical epithelium increases in cases of cervical intraepithelial neoplasia (CIN) 1 and 2.
  • This increase is associated with higher blood plasma erythropoietin levels and activation of both pro- and anti-apoptosis pathways, as well as cellular proliferation in the cervical tissue.

Article Abstract

The blood plasma erythropoietin content, erythropoietin content, erythropoietin and cellular renovation markers expression in exocervical epithelium in reproductive aged women with normal peripheral red blood values were studied. It was determined that erythropoietin expression increased in exocervical epithelium activity (cervical intraepithelial neoplasia 1 and 2), combined with the increase of blood plasma erythropoietin level, activation of pro- and antiapoptosis programs and cellular proliferation processes in cervical epithelium.

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