[Condition of erythrocytes in intact and vagotomized rats of various age after massive hemorrhage].

Sharp massive hemorrhage (30-35 % of total amount of blood) in rats are accompanied by natural changes of morpho-functional characteristics of erythrocytes: diameter, the area, polarization, the factor of the form, integrated and specific optical density. Thus, in certain terms, after hemorrhage at young initially intact animals average diameter, the area, integrated optical density actually increase as well as the value of polarization and the factor of the form of erythrocytes growth. In vagotomized rats of the same age group, in reply to hemorrhage, the increase in value of the factor of the form only is obvious. In initially intact old animals in these conditions, an increase of integrated and specific optical density and of the factor of the form also takes place. In old vagotomized rats, the average diameter and the erythrocyte area accrue. Thus, the character and dynamics of response of erythrone in initially intact and vagotomized (through 14 days after operation) animals essentially differ and have certain features dependent on age. Thus, in young initially intact rats, the most expressed changes are marked in 3-10 hours whereas in vagotomized animals of the same age group - in 3 and 96 hours after hemorrhage. In old initially intact rats, the greatest deviations of the investigated parameters are observed in 3 and 96 hours, in the vagotomized animals - in 3 and 24 hours.