AI Article Synopsis
- 84 patients with recent heart attacks were tested using dipyridamole (D) for safety and effectiveness in finding viable heart tissue and diagnosing multi-vessel disease.
- The D-Echo identified residual ischemia in 41 patients (48.8%), while D-Thallium showed 49 patients (58.3%) affected, and only 30 patients (43.5%) tested positive on the exercise test.
- D-testing proved more accurate than exercise tests for diagnosing multi-vessel disease, particularly highlighting high specificity in D-echo and D-thallium tests.
Article Abstract
84 patients (pts) with recent first uncomplicated myocardial infarction underwent during the early post-infarction period, dipyridamole (D) test (EKG-ECHO-THALLIUM) and coronary arteriography in order to verify its feasibility, safety and usefulness in the detection of residual jeopardized but viable myocardium and in the diagnosis of multivessel disease. 69 pts performed a pre-discharge exercise test. During the execution of D test no major side effect occurred. The D-Echo was positive for residual ischemia in 41 pts (48.8%), the D-Thallium in 49 pts (58.3%) and the exercise test in 30 pts (43.5%). Both the imaging techniques allow the recognition of viable myocardium within the infarct zone (homozonal positivity) or outside the infarct zone (heterozonal positivity). The sensibility and specificity for multivessel disease are, respectively: with D-echo 50% and 100%; with D-thallium 60% and 100%; with exercise test 48% and 63%. D test has better diagnostic accuracy than exercise test in detecting multivessel disease; in particular we emphasized the excellent specificity of D-echo and D-thallium test. Poliparametric approach with D-test and exercise test gives a better stratification of the ischemic post-infarction risk.
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