Objective: To explore the isometric attachment site of knee lateral collateral ligament (LCL) in the femoral lateral condyle; to introduce the isometric reconstruction of knee lateral collateral ligament with the long head of biceps femoris tendon.
Methods: Among 16 patients with knee injury treated with isometric reconstruction of the lateral collateral ligament, 10 patients were male and 6 patients were female, with an average age of 38.4 years (ranged from 20 to 58 years). Twelve patients were chronic injuries, four patients were acute injuries, with an average duration of 5 days to 11 months. Eleven patients had simple LCL injury,3 patients had LCL injury combined with PCL injury, 2 patients had LCL injury combined with ACL injury. The middle one third of the long head of biceps femoris tendon was cut to be fixed to the isometic bony tunnel of the femoral lateral condyle. The lateral stability of the knee was evaluated mainly through varus stress test.
Results: The better isometric attachment site is from the anatomical caput fibulae attachment site or the middle one third of the long head of biceps femoris to the femoral lateral condyle to 8-10 mm in front of the anatomical femoral attachment site of the lateral collateral ligament. The average follow-up period was 13.5 months (ranged from 12 to 24 months). At the 12th month after operation, there was no varus instability in full extension. At 30 degrees flexion, one-grade varus instability was found in 2 patients. In varus stress test the lateral joint space increased less than 5 mm compared to the healthy side.
Conclusion: The method provided good stability for the knee and acquired satisfactory clinical results.
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J Pediatr Orthop
January 2025
Department of Pediatric Orthopedic Surgery, Hospital for Special Surgery, New York, NY.
Background: Medial meniscus ramp lesions (MMRLs) are commonly associated with anterior cruciate ligament (ACL) injuries and may increase the risk of graft failure after ACL reconstruction (ACLR) if undiagnosed or left untreated. Although MMRLs have been extensively reported in adults, there are limited studies describing them in pediatric patients undergoing ACLR. The purpose of this study was to perform a systematic review and meta-analysis to determine the pooled prevalence of and risk factors for MMRLs in pediatric patients with ACL injuries.
View Article and Find Full Text PDFACS Synth Biol
January 2025
Department of Chemical and Biomolecular Engineering (BK21 Four), Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.
We herein developed an ultrasensitive and rapid strategy to identify genomic nucleic acids by integrating a clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 13a (Cas13a) into our recently developed isothermal technique, nicking and extension chain reaction system-based amplification (NESBA) reaction. In this technique, named CESBA, the NESBA reaction isothermally produces a large amount of RNA amplicons from the initial target genomic RNA (gRNA). The RNA amplicons bind to the crispr RNA (crRNA) and activate the collateral cleavage activity of Cas13a, which would then cleave the reporter probe nearby, consequently producing the final signals.
View Article and Find Full Text PDFAm J Sports Med
January 2025
Integrative Neuromuscular Sport Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.
Background: The individual variation in on-snow performance outcomes after anterior cruciate ligament (ACL) reconstruction (ACLR) in elite alpine ski racers has not been reported and may be influenced by specific injury characteristics.
Purpose: To report the performance statistics of elite ski racers before and after ACLR and to identify surgical and athlete-specific factors that may be associated with performance recovery.
Study Design: Descriptive epidemiological study.
SICOT J
January 2025
Department of Orthopaedic Surgery, Joint Replacement Unit, Kuala Lumpur Hospital, Ministry of Health Malaysia, Jalan Pahang, 50586 Kuala Lumpur, Malaysia.
Introduction: Extraarticular deformity (EAD) with knee arthritis is a complex condition involving tri-planar bone deformity with pathological malalignment and chronic soft tissue contracture or laxity in the knee joint. Intraarticular correction by TKA, which was previously performed with conventional manual jig by mechanical alignment technique, had its limits and difficulties especially extensive soft tissue release and risk of jeopardizing the collateral ligaments. Robotic technology allows for reproducible and precise execution of surgical plan and allows adjustment to various new personalised alignment philosophy including functional alignment (FA).
View Article and Find Full Text PDFOrthop J Sports Med
January 2025
Department of Orthopaedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Background: The aim of surgical treatment for posterolateral rotatory instability (PLRI) of the elbow is to restore the integrity of the lateral ulnar collateral ligament (LUCL), with ligamentous reconstruction being the preferred option for recurrent symptomatic PLRI. However, there is no clinical evidence demonstrating the superiority of reconstruction versus repair. Treatment options currently depend on the cause of the LUCL injury and surgeon preference.
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