A short and convergent synthetic approach to new photoactivatable precursors of gamma-aminobutyric acid (GABA) is described. When photolyzed, the 'caged' GABA precursor efficiently releases GABA, as judged by depolarization measurements on the mammalian GABA(A) receptor.
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| http://dx.doi.org/10.1016/j.bmcl.2009.03.065 | DOI Listing |
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