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A fatal case of peritonitis due to colonic localization of acute myeloid leukemia.
Ann Hematol
January 2025
Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Myeloid sarcoma (MS) is an extramedullary localization of immature granulocyte cells that can occur in association with acute myeloid leukemia (AML). Gastrointestinal involvement is relatively common in MS, but exclusive colonic localization is a rare occurrence. Here, we report on a 53-year-old male patient affected by AML developing a severe abdominal pain caused by intestinal perforation requiring surgical intervention.
View Article and Find Full Text PDFImmunological differences between monophasic and biphasic synovial sarcoma with implications for immunotherapy.
Cancer Immunol Immunother
December 2024
Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands.
Article Synopsis
- Synovial sarcoma is a type of aggressive soft-tissue cancer with limited response to current immunotherapies, highlighting the need for better understanding of the immune cells in its tumor microenvironment.
- Researchers studied 41 patients to analyze the relationship between immune cell types, tumor subtype (biphasic vs. monophasic), disease progression, and response to treatments like chemotherapy.
- Findings indicated that biphasic synovial sarcomas had a higher presence of immune cells, particularly T cells, which correlated with better patient survival, suggesting they may respond more favorably to immunotherapies.
A Case of Parasitic Leiomyoma in the Sigmoid Mesentery Following Total Laparoscopic Hysterectomy.
Cureus
November 2024
Obstetrics and Gynecology, Tama-Hokubu Medical Center, Higashimurayama, JPN.
Parasitic leiomyoma (PL) develops when fragments of a morcellated uterine leiomyoma, during procedures such as laparoscopic myomectomy (LM) or total laparoscopic hysterectomy (TLH), adhere to other tissues. We recently encountered a case where PL developed in the mesentery of the sigmoid colon following TLH. A 51-year-old woman had previously undergone TLH with in-abdominal morcellation.
View Article and Find Full Text PDFDesmoplastic Small Round Cell Tumor: a study of CT, MRI, PET/CT multimodal imaging features and their correlations with pathology.
BMC Med Imaging
December 2024
Department of Radiology, The First Affiliated Hospital of Xiamen University, 55 Zhenhai Road, Xiamen, 361000, People's Republic of China.
Purpose: Exploring the computed tomography (CT), magnetic resonance imaging (MRI), and fluorodeoxyglucose positron emission tomography (FDG-PET)/CT Multimodal Imaging Characteristics of Desmoplastic Small Round Cell Tumor (DSRCT) to enhance the diagnostic proficiency of this condition.
Methods: A retrospective analysis was performed on clinical data and multimodal imaging manifestations (CT, MRI, FDG-PET/CT) of eight cases of DSRCT. These findings were systematically compared with pathological results to succinctly summarize imaging features and elucidate their associations with both clinical and pathological characteristics.
Association of cutaneous leiomyosarcoma with subsequent primary malignancies: a population-based analysis.
Arch Dermatol Res
December 2024
Department of Dermatology, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
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