This talk, given as an introduction to a symposium organised to honor André Calas, calls forth his personality, recalls the major events in his career and summarizes the evolution of his research.
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Expression characteristics of in citrus and analysis of its interacting protein.
Plant Signal Behav
December 2025
School of Medical Technology, Chongqing Three Gorges Medical College, Chongqing, China.
The most damaging disease affecting citrus globally is Huanglongbing (HLB), primarily attributed to the infection by ' asiaticus' (Las). Based on comparative transcriptome data, two cellulose synthase (CESA) genes responsive to Las infection induction were screened, and one gene cloned with higher differential expression level was selected and named . we verified the interaction between CsCESA1 and citrus exopolysaccharide 2 (CsEPS2) proteins.
View Article and Find Full Text PDFGenetic and physiological characteristics of edited citrus and their impact on HLB tolerance.
Front Genome Ed
December 2024
Department of Horticultural Sciences, Citrus Research and Education Center, University of Florida, Lake Alfred, FL, United States.
Article Synopsis
- Huanglongbing (HLB) disease, triggered by the bacterium Liberibacter asiaticus, poses a serious threat to citrus production with no existing cure, making the development of resistant cultivars essential.
- Researchers focused on the NONEXPRESSOR OF PATHOGENESIS-RELATED GENES (NPR) family, specifically modifying NPR1 and NPR3 genes in sweet orange trees to improve HLB resistance.
- The genome-edited sweet orange varieties showed enhanced vigor compared to wild-type trees under greenhouse conditions, suggesting that targeted gene editing can help in developing HLB-tolerant citrus plants, although further field tests are required to confirm these results.
Association of exposure to second-hand smoke during childhood with blood DNA methylation.
Environ Int
January 2025
ISGlobal, Barcelona, Catalonia, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Catalonia, Spain; Centro de investigación biomédica en red en epidemiología y salud pública (CIBERESP), Madrid, Spain.
Introduction: By recent estimates, 40% of children worldwide are exposed to second-hand smoke (SHS), which has been associated with adverse health outcomes. While numerous studies have linked maternal smoking during pregnancy (MSDP) to widespread differences in child blood DNA methylation (DNAm), research specifically examining postnatal SHS exposure remains sparse. To address this gap, we conducted epigenome-wide meta-analyses to identify associations of postnatal SHS and child blood DNAm.
View Article and Find Full Text PDFPerformance of serum IL-18 levels for the follow-up of patients with familial Mediterranean fever.
J Allergy Clin Immunol Pract
December 2024
Department of Internal Medicine, Tenon Hospital, DMU 3ID, Sorbonne Université-Assistance Publique Hôpitaux de Paris, Paris, France; CEREMAIA (National reference center for autoinflammatory diseases ad AA amyloidosis), Paris, France; INSERM, UMRS 1155 UPMC, hôpital Tenon, Paris, France; INSERM U938, Paris, France. Electronic address:
Identification of CAP genes in finger lime (Citrus australasica) and their role in plant responses to abiotic and biotic stress.
Sci Rep
November 2024
Department of Horticultural Sciences, Citrus Research and Education Center, University of Florida, Lake Alfred, FL, USA.
Article Synopsis
- The study analyzes cysteine-rich secretory proteins and PR1-like genes in finger lime, focusing on their response to Huanglongbing disease.
- CaCAP2 gene showed a dramatic increase in expression during infection compared to sweet orange, indicating its importance in the plant's defense.
- The research also highlights the CAP2 gene's role in stress management and reveals genetic differences between finger lime and sweet orange that may affect their responses to environmental stresses.
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