[Role of exogenic precursors in formation of surface-active substances during cultivation Rhodoococcus erythiropolis EK-1 on ethanol].

A possibility to intensify synthesis of surfactants of Rhodococcus erythropolis EK-1 under the presence of citrate (lipid synthesis regulator) and fumarate (gluconeogenesis precursor) has been shown. A 40-100% increase of indices of surfactants synthesis with introduction of cytrate (0.1%) and fumerate (0.2%) in the beginning of the stationary producer growth phase is determined by activation of gluconeogenetic branch of metabolism and by intensification of lipids synthesis that was evidenced by the 1.4-1.5-fold and 3.4-3.6-fold increase of isocitrate liase and phosphoenolpyruvate synthetase activities, respectively, as well as by a 1.5-1.6-fold decrease of activity of isocitrate dehydrogenase. The paper is presented in Russian.