The paper considers the age-specific features of the clinical course of tropical malaria in children in Tadjikistan. Tropic malaria in children, those of young age in particular, is characterized by the acute onset, polymorphism of clinical manifestations, high fever of mainly abnormal type, and hepatosplenomegaly. Tropical malaria takes the most severe course in children of the first three years. The severity of the disease is due to the development of the toxic syndrome, cerebral disorders, and hemolytic anemia. An association has been seen between the onset of etiotropic treatment and the degree of tropic malaria: the earlier antimalaria therapy is initiated, the milder the disease is.

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