Castleman disease is a lymphocytic hyperplastic disease that is also known as angiofollicular lymphoid hyperplasia or giant lymph node hyperplasia. It occurs mainly in the mediastinum but rarely in the face. Our experience is a case of a 65-year-old man who had a slow-growing, nontender temporal mass for 1 year. Computed tomographic scans showed a 6.0 x 2.5 x 4.5-cm, homogenous and moderately enhanced soft tissue mass in the left temporal region. The mass was excised with caution to avoid injuries to the superficial temporal artery and facial nerve. Frozen section showed lymphoid hyperplasia lesion without malignancy. To the best of our knowledge, this is the first case of Castleman disease that presented in the temporal region; thus, for the first time, we report this case along with the review of the literature.
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http://dx.doi.org/10.1097/SCS.0b013e3181a14c19 | DOI Listing |
J Clin Exp Hematop
December 2024
Division of Pathology and Laboratory Medicine, JA Suzuka General Hospital, Suzuka, Mie, Japan.
A 72-year-old male patient presented fatigue, anemia, elevated total protein, IgG, IgG4, IL-6, and vascular endothelial growth factor (VEGF) levels. Initial diagnostics suspected multiple myeloma. A plane computed tomography (CT) scan showed pneumonia and the enlargement of generalized lymph nodes.
View Article and Find Full Text PDFJ Clin Exp Hematop
December 2024
Department of Radiology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
This study retrospectively evaluated the computed tomography (CT) findings of idiopathic multicentric Castleman disease (iMCD) at a single center and compared the CT findings of iMCD-TAFRO with those of iMCD-non-TAFRO. CT images obtained within 30 days before diagnostic confirmation were reviewed for 20 patients with iMCD (8 men and 12 women, mean age 52.8 ± 12.
View Article and Find Full Text PDFIntern Med
December 2024
Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Japan.
Front Med (Lausanne)
December 2024
Department of Hematology, Xuanwu Hospital, Capital Medical University, Beijing, China.
POEMS syndrome is a complex and rare hematological disease involving multiple physiological systems. According to the currently accepted diagnostic criteria for POEMS syndrome, polyneuropathy is one of the primary mandatory criteria. A patient presented with M protein, Castleman disease (CD), elevated vascular endothelial growth factor (VEGF), extravascular volume overload, and endocrinopathy.
View Article and Find Full Text PDFCurr Med Imaging
December 2024
Department of Vascular Neurosurgery, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez", 14267, Mexico City, Mexico.
Background: Castleman disease (CD) is a rare lymphoproliferative disorder, with intracranial involvement being exceedingly rare. Unicentric Castleman disease (UCD) is typically benign and localized, but its presentation can mimic other intracranial pathologies, complicating diagnosis.
Case Description: We reported a 52-year-old woman who presented with progressive headaches and language disturbances.
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