As burn wound sepsis continues to be one of the most common causes of death in burn patients, it is important to note the trend of increased involvement of fungal pathogens. Very little exists in the literature regarding management of such fungal infections. We report invasive cutaneous mucormycosis involving the face of an extensively burned patient with no prior medical history that would otherwise predispose her to such infection. Diagnosis and management are discussed leading to eventual eradication of the Mucor and survival of our patient.
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http://dx.doi.org/10.1097/BCR.0b013e3181a28d2f | DOI Listing |
J Educ Health Promot
September 2024
Department of Psychiatry, NIMHANS Bangalore, Karnataka, India.
A sudden surge in the cases of mucormycosis forced India's coronavirus disease 2019 task force to issue evidence-based advisory on the disease. Severity was seen as comparatively high among diabetic and immuno-compromised individuals. Surgical procedures leading to scars of incision and disfigurement of the face might trigger dissatisfaction with body image and poor mental health.
View Article and Find Full Text PDFJ Burn Care Res
September 2024
Division of Surgical Critical Care, Department of Surgery, Upstate Medical University, Syracuse, NY 13202, USA.
Mucormycosis is an uncommon infection but is increasing in prevalence. Cutaneous disease is associated with burns and traumatic injuries. Cutaneous mucormycosis is the least deadly form but mortality is still approximately 36%.
View Article and Find Full Text PDFKey Clinical Message: Immunosuppression from B-acute lymphoblastic leukemia (B-ALL) chemotherapy and a preceding COVID-19 infection may predispose patients to rare complications such as rhino-orbital mucormycosis. Hence, a high index of suspicion should be maintained by physicians (and oncologists) if patients undergoing B-ALL treatment present with orofacial symptoms and ophthalmological manifestations such as peri-orbital swelling, ophthalmoplegia, and loss of vision, suggestive of infection.
Abstract: Mucormycosis is a severe fungal infection that poses significant mortality and morbidity risks, particularly in immunocompromised individuals.
BMC Neurol
May 2024
Iranian Center of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Background: Progressive multifocal leukoencephalopathy (PML) is a rare and fatal opportunistic viral demyelinating infectious disease of the central nervous system (CNS). There are various clinical presenting symptoms for the disease.
Case Presentation: This paper presents a clinical case of PML in a patient with B-Chronic lymphocytic leukemia (B-CLL), previously treated with Chlorambucil, later complicated later with COVID-19 and mucormycosis.
J Med Virol
April 2024
Department of Medicine, AIIMS, New Delhi, Delhi, India.
Coronavirus disease 2019 (COVID-19) associated mucormycosis (CAM) was reported predominantly from India during the second wave of COVID-19 and has a high mortality rate. The present study aims to understand the fungal community composition of the nasopharyngeal region of CAM-infected individuals and compare it with severe COVID-19 patients and healthy controls. The fungal community composition was decoded by analyzing the sequence homology of the internal transcribed spacer-2-(ITS-2) region of metagenomic DNA extracted from the upper respiratory samples.
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