Objectives: It is recognized that ethnic group is important in describing differences in infection and disease, but is often not routinely available to surveillance systems. Computerized programmes, such as NamPehchan, can assign ethnicity according to name; however, sensitivity and positive predictive value (PPV) can vary. The aim of this study was to assess whether the sensitivity and PPV of NamPehchan had changed, after an observation that surnames previously associated with South Asians were increasingly reported as Black.
Study Design: Cross-sectional.
Methods: NamPehchan was used to classify women as South Asian using name, and compared with the gold standard (midwife-reported ethnicity). Sensitivity and PPV were calculated overall and by year. Frequency of infection by ethnic group was estimated.
Results: A total of 627 women positive for hepatitis B surface antigen were identified. The majority were from minority ethnic groups, particularly Asian. The overall sensitivity of NamPehchan was 74.5% and PPV was 68.5%. Almost 50% of Black African women were classified as South Asian by NamPehchan.
Conclusions: Immigration from African countries has reduced the sensitivity of NamPehchan in this group. Care is needed when using NamPehchan for groups which include Africans from Muslim areas, as misclassification is likely to occur.
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http://dx.doi.org/10.1016/j.puhe.2009.02.002 | DOI Listing |
BMC Public Health
January 2025
Department of Sports Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur, 50603, Malaysia.
Background: The increasing global and national prevalence of childhood obesity particularly among schoolchildren has warranted a more viable school-based obesity intervention. Apart from physical activity, nutrition is important in any obesity intervention package. This study examined the effects of the MyBFF@school program with nutrition education intervention (NEI) on nutrition knowledge and attitude of overweight and obese secondary schoolchildren.
View Article and Find Full Text PDFBackground: The gold standard Alzheimer's disease (AD) diagnosis with amyloid PET or CSF sampling is costly and not widely available. There is growing interest in utilizing plasma biomarker tests to provide etiologic clarity in the earliest symptomatic phases. We report the uptake, and biomarker results in relation to clinical diagnosis, of a brain amyloid probability score (APS) with the Precivity AD™ test (C2N Diagnostics) offered to clinician-selected eligible patients during their clinical workup in a memory clinic.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Univeristy of Washington School of Public Health, Seattle, WA, USA.
Background: Long-term exposure to ambient air pollution-including fine particulate matter <2.5µm in diameter (PM)-has previously been associated with incident dementia. As climate change drives longer and more intense wildfire seasons, exposure to PM produced by wildfires may be a unique and increasingly important risk factor for dementia.
View Article and Find Full Text PDFBackground: Selective corticolimbic vulnerability to tau pathology in Alzheimer's disease (AD) underlies clinicopathologic heterogeneity. The goal of this presentation will be to examine spatial heterogeneity of tangle distribution on a continuum through the utility of the corticolimbic index (CLix).
Method: We will discuss the development of CLix in the Florida Autopsied Multi-Ethnic (FLAME) cohort, which sought to collapse the spatial distribution of thioflavin-S tangle counts in AD (n=1361) to assign a continuum: hippocampal sparing with cortical predominance (<10), representative/typical (≥10 to <30), and limbic predominant with cortical sparing (≥30).
Alzheimers Dement
December 2024
University of California, San Francisco, San Francisco, CA, USA.
Background: APOE is highly pleiotropic, with the e4 allele the strongest genetic risk factor for late-onset Alzheimer's disease (AD) and associated with other cardiometabolic traits. The APOE*e4 allele demonstrates ancestry-specific differences in the risk for AD. Here, we investigated whether similar ancestry-specific effects are observed across other AD endophenotypes and modifiable risk factors for AD.
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