Self-calibrating pulse contour cardiac output: do validation studies really show its clinical reliability?

The present study was performed to test a new software version of the FloTrac/Vigileo using head-up-head-down tilting in post-cardiac surgery patients. Impressive improvements in Bland and Altman limits of agreement from 37.5% to 21.6% were recorded. The results, however could be attributed to a failure to produce a wide enough range of test circulatory conditions. A more rigorous test of performance is needed before any real conclusion concerning use of the FloTrac/Vigileo in clinical practice can be made.