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Lessons Learned Evaluating Ablative Fractional CO2 Laser for Burn-Related Donor Site Scars.
J Burn Care Res
March 2025
Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, District of Columbia, USA.
Hypertrophic scar (HTS) remains a comorbidity of burn injury, often requiring split thickness skin grafting (STSG) and resulting in symptomatic HTS at grafted sites and STSG donor sites (DS). Literature supports the use of ablative fractional CO2 laser (FLSR) to treat HTS, however many trials lack of control sites and tissue-level examinations. Given the widespread adoption of FLSR for HTS, delegation of non-treated scar sites for the sake of randomized controlled trial (RCT) is troubling for many clinicians.
View Article and Find Full Text PDFExperiencing fertility preservation in adolescence - a qualitative interview study indicating gender disparities in AYAs diagnosed with cancer.
Front Oncol
February 2025
Department of Obstetrics and Gynecology, Örebro University, Örebro, Sweden.
Introduction: Fertility counselling on options for fertility preservation is increasingly implemented for children and adolescents at time of cancer diagnosis. Sperm cryopreservation has been standard of care for male patients during several decades and the procedure is not expected to delay the onset of cancer treatment. However, oocyte cryopreservation in female adolescents remains controversial, the reasons include the need of ovarian stimulation, gynecological exams and interventions, in all a potentially distressing experience for patients without previous experience of this type of examination or without previous sexual debut.
View Article and Find Full Text PDFHybrid barn: the switch from a naturally to a mechanically ventilated turkey barn to protect from harmful bioaerosols.
Front Vet Sci
February 2025
Institute for Animal Hygiene, Animal Welfare and Farm Animal Behavior, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Introduction: Animal health is essential to ensure the highest level of animal welfare and to conserve resources. Especially in naturally ventilated barns, the airborne entry of pathogens is difficult to avoid. For instance, birds in naturally ventilated turkey barns are frequently infected by highly pathogenic avian influenza and the airborne route may play a role.
View Article and Find Full Text PDFFrequency and Predictors of Adolescent Worry for School Gun Violence In the United States: Findings from a Nationally Representative Study.
medRxiv
February 2025
Division of Adolescent Medicine, Indiana University School of Medicine, Indianapolis, IN.
Purpose: While school gun violence (SGV) incidents in the United States (U.S.) have risen sharply over the past decade, limited research has examined adolescent worries about SGV.
View Article and Find Full Text PDFieGENES: A machine learning method for selecting differentially expressed genes in cancer studies.
J Biomed Inform
February 2025
Health Data Research Wales and Northern Ireland, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7AE, UK; The Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7AE, UK. Electronic address:
Gene selection is crucial for cancer classification using microarray data. In the interests of improving cancer classification accuracy, in this paper, we developed a new wrapper method called ieGENES for gene selection. First we proposed a parsimonious kernel machine regularization (PKMR) model by using ridge regularization in kernel machine driven classification to tackle multi-collinearity for the sake of stable estimates in high-dimensional settings.
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