AI Article Synopsis
- * Researchers are exploring spectroscopic techniques, specifically FTIR microspectroscopy, to improve the diagnosis and grading of prostate cancer.
- * A large patient study demonstrated that FTIR microspectroscopy, along with Principal Component Discriminant Function Analysis, can accurately grade prostate cancer tissues with high sensitivity and specificity.
Article Abstract
Prostate cancer is the most common gender specific cancer. The current gold standard for diagnosis, histopathology, is subjective and limited by variation between different pathologists. The diagnostic problems associated with the correct grading and staging of prostate cancer (CaP) has led to an interest in the development of spectroscopic based diagnostic techniques. FTIR microspectroscopy used in combination with a Principal Component Discriminant Function Analysis (PC-DFA) was applied to investigate FTIR based histopathology for the diagnosis of CaP. In this paper we report the results of a large patient study in which FTIR has been proven to grade CaP tissue specimens to a high degree of sensitivity and specificity.
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| http://dx.doi.org/10.1002/jbio.200810062 | DOI Listing |
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