A flexible scanning fiber-optic endomicroscope using a miniature compound lens and a multimode-fiber (MMF) collector was developed for two-photon fluorescence (TPF) and second-harmonic generation (SHG) imaging. The compound lens consisted of a pair of aspherical lenses and exhibited reduced chromatic aberration compared with gradient-index lenses, thus increasing the TPF/SHG collection efficiency. The introduction of a short MMF collector at the distal end of the double-clad fiber of the endomicroscope further mitigated the adverse influence of chromatic aberration of the lens and enhanced the TPF/SHG collection efficiency. Both ray-tracing simulations and experiments on TPF imaging of fluorescent beads and SHG imaging of rattail tendon demonstrated approximately nine (approximately four) times improved collection efficiency for TPF (SHG) with the new endomicroscope design that utilized a compound lens and an MMF collector.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697571 | PMC |
| http://dx.doi.org/10.1364/ol.34.000953 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Natural Hydrogel-based Drug Delivery System: A Global Scenario, Current Development, and Future Prospective.
Curr Drug Deliv
January 2025
Department of Pharmaceutics, Y. B. Chavan College of Pharmacy, Aurangabad, India.
Pharmaceutical giants (e.g., Ashland, Bausch & Lomb, Johnson & Johnson, Medtronic, Neurelis, etc.
View Article and Find Full Text PDFThe imperative to improve the well-being of graduate medical education (GME) trainees has been well documented. While existing interventions have largely centered on increasing individual trainee resilience, less focus has been on the role of national health policy, economics, and the overall U.S.
View Article and Find Full Text PDFGrowing in red: impact of different light spectra and lighting conditions on lentil microgreens growth in vertical farming.
Front Plant Sci
December 2024
Laboratory of Advanced Studies in Vertical Agriculture, Goiano Federal Institute of Education, Science and Technology, Rio Verde, Brazil.
Vertical Farming Systems (VFS) emerge as an approach to optimize plant growth in urban and controlled environments, by enabling sustainable and intensive production in reduced spaces. VFS allow for greater control over growing conditions, such as light, temperature and humidity, resulting in higher quality crops and with less use of resources, such as water and fertilizers. This research investigates the effects of different lighting regimes (Constant and Gaussian) and spectral qualities (white, RBW, blue and red) on the growth, photosynthesis, and biomass accumulation of lentil microgreens () in VFS.
View Article and Find Full Text PDFDo strigolactones play a role in the ascent and attachment behavior of ?
Plant Signal Behav
December 2025
Department of General Psychology, University of Padova, Padova, Italy.
Article Synopsis
- Strigolactones (SLs) are important plant signaling compounds that help coordinate growth between roots and shoots.
- The study investigates how SLs affect the climbing behavior of pea plants by analyzing the movement of their tendrils through 3D kinematical methods.
- Results show that mutant pea plants lacking SLs exhibit disoriented and less energetic climbing behaviors, highlighting the significance of SLs in plant behavior and communication.
[Peptidergic regulation of expression of cellular aging marker proteins in buccal epithelium.].
Adv Gerontol
January 2025
Belgorod State National Research University, 85 build. 10 Pobedy str., Belgorod 308015, Russian Federation, e-mail:
Article Synopsis
- The review summarizes long-term research by the Saint-Petersburg Institute of Bioregulation and Gerontology on the biological activity of peptide bioregulators and compares findings from domestic and international studies.
- Russian scientists have taken the lead in using buccal epithelium as a diagnostic marker for age-related diseases, highlighting their significant contributions in this field.
- The research reveals that peptides from the epiphysis can enhance melatonin secretion and influence circadian rhythms in the elderly by regulating gene expression and reducing harmful protein synthesis, suggesting their potential as therapeutic agents for age-related issues.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!