Background: The use of injections to reduce localized fat deposits, first discovered in Italy in the 1980s, was popularized in South America and further developed by the author.
Objective: The objective of this study was to demonstrate the efficacy of injection lipolysis in the reduction of localized fat deposits.
Methods: A study group of 441 patients received from 1 to 4 injections of a phosphatidylcholine mixture developed by the author for treatment of localized fat deposits in the upper and lower abdomen, hips, thighs, upper arms, and face.
Results: After treatment with injection lipolysis of up to 100 mL of injectable mixture, containing a maximum of 2500 mg phosphatidylcholine, fat deposits showed an average circumferential reduction per application f.i. upper belly 3.7 cm, lower belly 3.9 cm, thighs 1.9 cm, upper arms 1.6 cm. Very good success was seen in facial treatments. No patient showed irregularities, dimples or any serious side effect after treatment. No re-enlargement of fat deposits was reported during the time of the study.
Conclusions: All patients showed remarkable reductions of fat deposits treated with injection lipolysis. Using the correct technique, injection lipolysis is a safe and efficacious alternative to lipoplasty on smaller areas for patients objecting to, or unable to undergo, surgery. It is not a replacement for a necessary change of lifestyle, nor is it a method of weight reduction or a treatment for obesity. The ideal patient is one with small to medium fat deposits that cannot be reduced by exercise and diet.
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http://dx.doi.org/10.1016/j.asj.2006.01.008 | DOI Listing |
Nutrients
January 2025
Department of Food Science and Nutrition, Dankook University, Cheonan 31116, Republic of Korea.
Background/objectives: Obesity is a key factor in metabolic syndrome (MetS) development. Consumption of a high-fat diet (HFD) accelerates the onset of obesity and associated metabolic complications. (PB) has been traditionally utilized in Korean medicine for its antioxidant, anti-diabetic, anticancer, and hepatoprotective effects.
View Article and Find Full Text PDFBiomolecules
January 2025
Department of Physiology and Pathophysiology, St. Boniface Hospital Albrechtsen Research Centre, Institute of Cardiovascular Sciences, Rady College of Medicine, Max Rady Faculty of Health Sciences, University of Manitoba, Rm. 3042, 351 Taché Avenue, Winnipeg, MB R2H 2A6, Canada.
Hypertension is one of the most common comorbidities in cardiometabolic diseases, affecting nearly one third of adults. As a result, its pathophysiological mechanisms have been studied extensively and are focused around pressure natriuresis, the renin-angiotensin system (RAS), the sympathetic nervous system, oxidative stress, and endothelial dysfunction. Additionally, hypertension secondary to other underlying etiologies also exists.
View Article and Find Full Text PDFBiomolecules
January 2025
College of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Excessive abdominal fat deposition in chickens disadvantages feed conversion, meat production, and reproductive performance. Intramuscular fat contributes to meat texture, tenderness, and flavor, serving as a vital indicator of overall meat quality. Therefore, a comprehensive analysis of the regulatory mechanisms governing differential deposition of abdominal versus intramuscular fat is essential in breeding higher-quality chickens with ideal fat distribution.
View Article and Find Full Text PDFCardiovasc Diabetol
January 2025
Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland, UK.
Background: Obesity, a major risk factor for cardiovascular disease (CVD), is associated with hypertension and vascular dysfunction. Perivascular adipose tissue (PVAT), a metabolically active tissue surrounding blood vessels, plays a key role in regulating vascular tone. In obesity, PVAT becomes dysregulated which may contribute to vascular dysfunction; how sex impacts the remodelling of PVAT and thus the altered vascular contractility during obesity is unclear.
View Article and Find Full Text PDFNat Genet
January 2025
Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Human adipose depots are functionally distinct. Yet, recent single-nucleus RNA sequencing (snRNA-seq) analyses largely uncovered overlapping or similar cell-type landscapes. We hypothesized that adipocyte subtypes, differentiation trajectories and/or intercellular communication patterns could illuminate this depot similarity-difference gap.
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