A new ellagitannin dimer named euscaphinin was isolated from the leaves of Euscaphis japonica (THUNB.) KANITZ. The structure of this dimer was determined on the basis of spectroscopic and chemical evidence. The resulting structure indicated that it was produced by intermolecular C-O oxidative coupling between the galloyl groups of molecules of 1(beta)-O-galloyl pedunculagin, the major ellagitannin of the leaves. The ellagitannins were not detected in the bark and wood part of the plant. This is the first example of the isolation of ellagitannins from Staphyleaceaeous plants.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1248/cpb.57.421 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Oenothein B from Eugenia uniflora leaves exerts pro-angiogenic effects by increasing VEGF and TNF-α levels.
Cytokine
October 2024
Laboratory of Radiobiology and Mutagenesis, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Goiás, Brazil. Electronic address:
Oenothein B (OeB), a dimeric ellagitannin with a macrocyclic structure, is reported to have beneficial effects, including antioxidant, antitumor, antiviral, and antimutagenic effects, on human health. Despite the remarkable properties of OeB, its role in neovascularization process has not yet been evaluated. Thus, this study aimed to evaluate the angiogenic activity of OeB using a chorioallantoic membrane (CAM) assay at different concentrations (6.
View Article and Find Full Text PDFExtraction of bioactive compounds from pecan nutshell: An added-value and low-cost alternative for an industrial waste.
Food Chem
September 2024
Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Química Orgánica, Buenos Aires, Argentina; CONICET-Universidad de Buenos Aires, Centro de Investigaciones en Hidratos de Carbono (CIHIDECAR), Buenos Aires, Argentina. Electronic address:
The pecan nutshell [Carya illinoinensis (Wangenh) C. Koch] (PNS) is a source of bioactives with important beneficial properties for the human health. PNS represents between 40-50 % of total mass of the nut, resulting as waste without any added value for the food industry.
View Article and Find Full Text PDF[Dynamic Chemistry of Tannins].
Yakugaku Zasshi
February 2024
Institute of Biomedical Sciences (Pharmaceutical Sciences), Nagasaki University.
Tannins are a group of polyphenols that possess the ability to precipitate proteins, causing an undesirable astringent taste by interacting with salivary peptides. This interaction deactivates the digestive enzymes; therefore, tannins are considered as plant defense substances. The health benefits of tannins and related polyphenols in foods and beverages have been demonstrated by biological and epidemiological studies; however, their metabolism in living plants and the chemical changes observed during processing of foods and medicinal herbs raises some questions.
View Article and Find Full Text PDFIdentification of Antioxidative Hydrolyzable Tannins in Water Chestnut.
Molecules
September 2023
Department of Pharmacognosy, College of Pharmaceutical Sciences, Matsuyama University, 4-2 Bunkyo-cho, Matsuyama 790-8578, Ehime, Japan.
Despite the various biological activities exhibited by water chestnut (the fruit of the genus), the phenolic compounds present in its extract require comprehensive characterization. Accordingly, we analyzed a 80% methanol extract of commercially available water chestnut and identified a new hydrolyzable tannin dimer termed trapadin A. Additionally, 22 known compounds, including 10 hydrolyzable tannin monomers and 2 dimers, were also detected in the extract.
View Article and Find Full Text PDFChemopreventive effect and induction of DNA repair by oenothein B ellagitannin isolated from leaves of in Swiss Webster treated mice.
J Toxicol Environ Health A
December 2023
Institute of Biological Sciences, Federal University of Goiás, Goiânia-GO, Brazil.
Oenothein B (OeB) is a dimeric ellagitannin with potent antioxidative, antitumor, immunomodulatory, and anti-inflammatory properties. Despite the promising activities of OeB, studies examining the genotoxic or protective effects of this ellagitannin on DNA are scarce. Therefore, to further comprehensively elucidate the chemopreventive profile of OeB, the aim of this study was to evaluate the mutagenic and antimutagenic actions of OeB using strains with the Ames test.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!