The reagent-free C(2)-C(7) thermal cyclization of a nonconjugated aryl-yne-carbodiimide yielded a dibenzo[b,g][1,8]naphthyridine derivative, whose congeners are known to possess fascinating pharmacological properties. This is the first heteroaromatic compound prepared by the thermal cycloaromatization of "nonconjugated" aryl-ynes.
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| http://dx.doi.org/10.1248/cpb.57.393 | DOI Listing |
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