The velocity distributions in the clearance gap of the Kyoto-NTN biocentrifugal ventricular assist device model were measured by laser Doppler velocimetry (LDV) at three inlet flow conditions, namely operating, fully opened, and fully closed conditions. The results obtained have a similar trend as in the earlier measurements using air as medium and the hot-wire probe, a washout mechanism that is a segment of fluids in the gap situated from theta = 60 degrees to 220 degrees, has a larger radial velocity component flowing toward the eye of the pump, as compared to other regions in the gap where the tangential velocity component is dominant. It is essential to have a good washout for the leakage flow through the clearance gap between the stationary casing and the impeller of the pump so that the blood will not keep on circulating in the gap but is washed out to the eye in order to reduce the chances of being destroyed. Although the detailed velocity distributions are not the same, this should be due to the minor fabrication differences between two pump models. The current noninvasive LDV measurements should have a better representation of the actual flow field than the earlier studies due to the blood analog being used as the flow medium. Furthermore, as compared to the methods used in the earlier studies, there is basically no modification of the pump geometry in the present measurement.

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1525-1594.2009.00722.xDOI Listing

Publication Analysis

Top Keywords

clearance gap
12
laser doppler
8
doppler velocimetry
8
biocentrifugal ventricular
8
ventricular assist
8
assist device
8
device model
8
velocity distributions
8
velocity component
8
earlier studies
8

Similar Publications

Purpose: Redox homeostasis plays a key role in regulating the overall health and development of organisms. This study aimed to develop a compact and mobile continuous-wave (CW) electron paramagnetic resonance (EPR) imager to facilitate stable, highly sensitive fast three-dimensional (3D) whole-body imaging of nitroxide-infused mice.

Methods: A multiturn loop gap resonator with a diameter of 30 mm and length of 35 mm was designed for whole-body EPR imaging.

View Article and Find Full Text PDF

Impact of periampullary diverticulum on endoscopic retrograde cholangiopancreatography: bridging the gap between fiction and reality.

Prz Gastroenterol

September 2024

Department of Hepatology and Gastroenterology, National Liver Institute, Menoufia University, Shebeen El-Koum, Menoufia, Egypt.

Introduction: Periampullary diverticulum (PAD) is frequently discovered in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP). Studies have yielded conflicting results regarding its impact on the technical success of ERCP and post-ERCP complications.

Aim: This study aims to assess the success and safety of ERCP in patients with PAD.

View Article and Find Full Text PDF

Background: Strong partnerships, community engagement, and multisectoral collaboration in the health supply chain are synergistic pillars towards achieving universal health coverage. In Rwanda, the health supply chain involves the collaboration of various stakeholders, including distributors, manufacturers, wholesalers, and customers. However, since the eruption and ending of COVID-19, there has not been any study to assess stakeholders' perspectives on the status of the benefits, challenges, and best practices of collaborative partnerships among health supply chain stakeholders in Rwanda.

View Article and Find Full Text PDF

Background: Alterations in sensory perception, a core phenotype of autism, are attributed to imbalanced integration of sensory information and prior knowledge during perceptual statistical (Bayesian) inference. This hypothesis has gained momentum in recent years, partly because it can be implemented both at the computational level, as in Bayesian perception, and at the level of canonical neural microcircuitry, as in predictive coding. However, empirical investigations have yielded conflicting results with evidence remaining limited.

View Article and Find Full Text PDF

Evaluating student understanding of core pharmacokinetic concepts.

Eur J Pharmacol

January 2025

Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Australia. Electronic address:

Both educators and graduates have expressed concern about a perceived pharmacology knowledge gap that includes difficulty applying fundamental principles to clinical and research problems. Consequently, we sought to determine the extent to which current students can explain the meaning of, and appropriately apply, a subset of core concepts, and to identify any misconceptions arising from the responses. Of the twenty-four pharmacology core concepts arising from the recent international collaboration, four pharmacokinetic concepts were chosen, namely drug bioavailability, drug clearance, volume of distribution, and steady-state concentration.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!