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Unlabelled: The most frequent cause of nephritic syndrome in the pediatric population is acute post-infectious glomerulonephritis (PIGN). A rare complication is posterior reversible encephalopathy syndrome (PRES), characterized by subcortical vasogenic cerebral edema associated with variable neurological symptoms. The development of autoimmune hemolytic anemia is an atypical clinical presentation.

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Epidemiology of kidney biopsy from regional referral center in Romania: 10-year review.

Rom J Intern Med

December 2024

Department of Nephrology, University of Medicine, and Pharmacy "Iuliu Hatieganu" Cluj-Napoca, 8 Victor Babeș Street, 400012 Cluj-Napoca, Romania.

Purpose: To provide epidemiologic data on kidney biopsy from Romania.

Methods: Retrospective observational study of kidney biopsy records for adult patients from a referral center in the north-western part of Romania, reported for 2014-2023.

Results: 556 biopsies were performed, corresponding to an incidence of 12 biopsies/m person-year with over 50% increase over the last reported year.

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Background: HIV infection is associated with a significant kidney disease burden. This study is aimed to screen for kidney disease in all HIV patients on highly active anti retroviral therapy (HAART), study clinico-histological correlation, and assess the impact of early diagnosis on the clinical course.

Materials And Methods: It was a prospective, longitudinal study done in a tertiary care hospital.

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Article Synopsis
  • - Acute kidney injury can often be a side effect of certain medications, including antibiotics like amoxicillin.
  • - A specific case is reported where a patient experienced acute renal failure twice due to amoxicillin, which was linked to an immuno-allergic reaction.
  • - The diagnosis was validated through kidney biopsy and was further confirmed when the patient was re-exposed to amoxicillin.
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Article Synopsis
  • A study in Romania reviewed 1,254 adults with biopsy-proven glomerulopathies (GP) from 2008 to 2017 to assess changes in frequency and causes for kidney biopsies (KB).
  • The research found that while nephrotic syndrome was a common reason for KB, its occurrence decreased significantly over the decade, with older patients showing more advanced kidney damage and chronic kidney function decline.
  • Additionally, there was a notable increase in cases of diabetic nephropathy and crescentic glomerulonephritis, suggesting changes in diagnostic practices rather than an actual rise in GP prevalence among older adults.
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