AI Article Synopsis
- The study aimed to assess the clinical outcomes of patients who required intra-operative blood transfusions by examining tissue perfusion markers.
- A total of 61 adult patients undergoing surgery were evaluated, revealing that Scv02 was the most effective tissue perfusion marker for predicting mortality, with a cut-off point of 80%.
- Findings indicated that patients with Scv02 levels at or below 80% experienced significantly lower mortality rates and fewer postoperative complications compared to those with higher Scv02 levels, suggesting that adequate perfusion is crucial for better clinical outcomes following blood transfusions.
Article Abstract
Purpose: The aim this study was to evaluate the clinical outcome of patients needing intra-operative blood transfusion by tissue perfusion markers.
Methods: A prospective single center cohort study. Adult patients needing blood transfusion during the intra-operative period were recruited.
Results: This study included 61 patients. At the time of blood transfusion the hemoglobin level was 8.4+/-1.8 g/dL. Scv02 has been the best tissue perfusion marker to determine mortality, compared with hematemetric values and other tissue perfusion markers, with a cut-off point at ROC curve equal to 80% (AUC=0.75; sensitivity=80%; specificity=65.2%). Patients who received blood transfusion and had Scv02
Conclusions: In major surgeries, Scv02 appears to be an important variable to be taken into consideration to decide for or against blood transfusion, since blood transfusion with adequate perfusion, reflected by Scv02>80%, are associated with worse clinical outcomes.
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| http://dx.doi.org/10.1016/j.jcrc.2009.01.004 | DOI Listing |
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