Mechanism of the cytostasis mediated by blood unstimulated neutrophils on syngeneic rat colon cancer cells.

In Vivo

Research Group on Human and Experimental Digestive Tumours, INSERM U252, Faculty of Medicine, Dijon, France.

Published: December 1991

Non-activated polymorphonuclear neutrophils (PMNs) isolated from the blood of non-stimulated rats were spontaneously and selectively cytostatic in vitro against a syngeneic colon cancer cell line. In this experimental model, the mechanism of PMN-mediated cytostasis did not depend on oxidative metabolites, but involved soluble factor(s), possibly granule proteases.

Download full-text PDF

Source

Publication Analysis

Top Keywords

colon cancer
8
mechanism cytostasis
4
cytostasis mediated
4
mediated blood
4
blood unstimulated
4
unstimulated neutrophils
4
neutrophils syngeneic
4
syngeneic rat
4
rat colon
4
cancer cells
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!